NCOA3 Recombinant Protein (OPCD05602)

Catalog No: OPCD05602

NCOA3 Recombinant Protein (OPCD05602) using SDS-PAGE

NCOA3 Recombinant Protein (OPCD05602) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Gly1023-Ala1304
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 97%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: NCOA3
• Gene Full Name: nuclear receptor coactivator 3
• Alias Symbols: ACTR;AIB1;AIB-1;amplified in breast cancer 1 protein;bHLHe42;CAGH16;CBP-interacting protein;class E basic helix-loop-helix protein 42;CTG26;KAT13B;nuclear receptor coactivator 3;pCIP;RAC3;receptor-associated coactivator 3;SRC3;SRC-3;steroid receptor coactivator protein 3;thyroid hormone receptor activator molecule 1;TNRC14;TNRC16;TRAM-1.
• NCBI Gene Id: 8202
• Protein Name: Nuclear receptor coactivator 3
• Description of Target: Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Plays a central role in creating a multisubunit coactivator complex, which probably acts via remodeling of chromatin. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ER), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Displays histone acetyltransferase activity. Also involved in the coactivation of the NF-kappa-B pathway via its interaction with the NFKB1 subunit.
• Uniprot ID: Q9Y6Q9
• Protein Accession #: NP_001167559.1
• Nucleotide Accession #: NM_001174088.1
• Protein Size (# AA): Gly1023~Ala1304
• Molecular Weight: 40kDa