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Catalog No: OASG03217
Size:100 uL
Price: $239.00
SKU
OASG03217
Availability: Domestic: within 2-3 weeks delivery | International: 2-3 weeks
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NCOA2 Antibody (Phospho-Ser736) (OASG03217)

Datasheets/ManualsPrintable datasheet for anti-NCOA2 (OASG03217) antibody
Product Info
Predicted Species ReactivityHuman
Product FormatLiquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ApplicationWB, IHC
Reconstitution and StorageStore at -20C. Avoid repeated freeze/thaw cycles.
ImmunogenSynthesized peptide derived from human GRIP-1 around the phosphorylation site of S736. Location: 680-760aa.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration1 mg/ml
Target Post-Translational ModificationPhospho-Ser736
SpecificityPhospho-GRIP-1 (S736) Polyclonal Antibody detects endogenous levels of GRIP-1 protein only when phosphorylated at S736.
Application InfoWB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000;
Gene SymbolNCOA2
Gene Full Namenuclear receptor coactivator 2
Alias SymbolsSRC2, TIF2, GRIP1, KAT13C, NCoA-2, bHLHe75
NCBI Gene Id10499;
Description of TargetThe NCOA2 gene encodes nuclear receptor coactivator 2, which aids in the function of nuclear hormone receptors. Nuclear hormone receptors are conditional transcription factors that play important roles in various aspects of cell growth, development, and homeostasis by controlling expression of specific genes. Members of the nuclear hormone receptor superfamily, which includes the 5 steroid receptors and class II nuclear receptors (see below), are structurally characterized by 3 distinct domains: an N-terminal transcriptional activation domain, a central DNA-binding domain, and a C-terminal hormone-binding domain. Before the binding of hormone, steroid receptors, which are sometimes called class I of the nuclear hormone receptor family, remain inactive in a complex with heat-shock protein-90 (MIM 140571) and other stress family proteins. Binding of hormone induces critical conformational changes in steroid receptors that cause them to dissociate from the inhibitory complex, bind as homodimers to specific DNA enhancer elements associated with target genes, and modulate that gene's transcription. After binding to enhancer elements, transcription factors require transcriptional coactivator proteins to mediate their stimulation of transcription initiation (Hong et al., 1997 [PubMed 9111344]).[supplied by OMIM, Nov 2010]
Uniprot IDQ15596
Molecular Weight180 kDa
  1. What is the species homology for "NCOA2 Antibody (Phospho-Ser736) (OASG03217)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "NCOA2 Antibody (Phospho-Ser736) (OASG03217)"?

    This item is available "Domestic: within 2-3 weeks delivery | International: 2-3 weeks".

  3. What buffer format is "NCOA2 Antibody (Phospho-Ser736) (OASG03217)" provided in?

    This item is provided in "Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "NCOA2 Antibody (Phospho-Ser736) (OASG03217)"?

    This target may also be called "SRC2, TIF2, GRIP1, KAT13C, NCoA-2, bHLHe75" in publications.

  5. What is the shipping cost for "NCOA2 Antibody (Phospho-Ser736) (OASG03217)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "NCOA2 Antibody (Phospho-Ser736) (OASG03217)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "NCOA2 Antibody (Phospho-Ser736) (OASG03217)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "180 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "NCOA2 Antibody (Phospho-Ser736) (OASG03217)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "NCOA2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "NCOA2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "NCOA2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "NCOA2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "NCOA2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "NCOA2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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