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Catalog No: OPCD05598
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OPCD05598
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Datasheets/ManualsPrintable datasheet for NCL Recombinant Protein (OPCD05598)
Product Info
Predicted Species ReactivityHomo sapiens|Human
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
Residues: Lys388-Gln569
Isoelectric Point: 6.7
Subcellular Location: Nucleus, Cytoplasm
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 90%
SourceE.coli
TagN-terminal His Tag
Gene SymbolNCL
Gene Full Namenucleolin
Alias SymbolsC23;Nsr1;nucleolin;Protein C23.
NCBI Gene Id4691
Protein NameNucleolin
Description of TargetNucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats.
Uniprot IDP19338
Protein Accession #NP_005372.2
Nucleotide Accession #NM_005381.2
Protein Size (# AA)Lys388~Gln569
Molecular Weight24kDa
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