NBPF1 Antibody - C-terminal region (OASG04839)

Catalog No: OASG04839

Size:100 uL

Western Blot using 293

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB, IHC
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from the C-terminal region of human NBPF1/9/10/12/14/15/16/20. Location: 700-780aa.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Specificity: NBPF1/9/10/12/14/15/16/20 Polyclonal Antibody detects endogenous levels of NBPF1/9/10/12/14/15/16/20 protein.
• Application Info: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000;

Target Info

• Gene Symbol: NBPF1, NBPF14, NBPF15, NBPF9
• Gene Full Name: neuroblastoma breakpoint family, member 1
• Alias Symbols: AD2, NBG, AB13, AB14, AB23, NBPF
• NCBI Gene Id: 55672; 400818; 284565; 25832;
• Description of Target: This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number variations in the human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, mental retardation, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This gene family contains numerous pseudogenes.
• Uniprot ID: Q5TAG4, Q6P3W6, Q5SXJ2, Q3BBV0, Q3BBW0, Q3BBV1, Q8N660, Q5TI25
• Molecular Weight: 36 kDa