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Datasheets/Manuals | Printable datasheet for NANOG Antibody (OABF00311) |
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Predicted Species Reactivity | Human|Mouse|Porcine|Rat |
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Product Format | Liquid. Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. |
Clonality | Polyclonal |
Isotype | IgG |
Host | Rabbit |
Conjugation | Unconjugated |
Application | Enzyme-linked immunosorbent assay|Flow cytometry|Immunocytochemistry|Immunofluorescence|Immunohistochemistry-Frozen|Immunohistochemistry-Paraffin|Western blot |
Additional Information | Subcellular location: Nucleus |
Reconstitution and Storage | -20°C |
Immunogen | KLH conjugated synthetic peptide derived from mouse Nanog |
Purification | Protein A Purified |
Concentration | 1 ug/ul |
Application Info | WB: 1:100 - 1000 IHC-P: : 1:100 - 500 |
Gene Symbol | Nanog |
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Gene Full Name | Nanog homeobox |
Alias Symbols | 2410002E02Rik;early embryo specific expression NK family;early embryo specific expression NK-type homeobox protein;ecat;ecat4;EN;ENK;ES cell-associated protein 4;homeobox protein NANOG;homeobox transcription factor Nanog. |
NCBI Gene Id | 71950 |
Protein Name | Homeobox protein NANOG |
Description of Target | Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal (PubMed:25825768). Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'. Binds to the POU5F1/OCT4 promoter (By similarity). Able to autorepress its expression in differentiating (ES) cells: binds to its own promoter following interaction with ZNF281/ZFP281, leading to recruitment of the NuRD complex and subsequent repression of expression. When overexpressed, promotes cells to enter into S phase and proliferation. |
Uniprot ID | Q80Z64 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "NANOG Antibody (OABF00311)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse|Porcine|Rat".
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How long will it take to receive "NANOG Antibody (OABF00311)"?
This item is available "3 to 5 business days.".
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What buffer format is "NANOG Antibody (OABF00311)" provided in?
This item is provided in "Liquid. Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "NANOG Antibody (OABF00311)"?
This target may also be called "2410002E02Rik;early embryo specific expression NK family;early embryo specific expression NK-type homeobox protein;ecat;ecat4;EN;ENK;ES cell-associated protein 4;homeobox protein NANOG;homeobox transcription factor Nanog." in publications.
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What is the shipping cost for "NANOG Antibody (OABF00311)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "NANOG Antibody (OABF00311)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "NANOG Antibody (OABF00311)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "NANOG Antibody (OABF00311)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "Nanog"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "Nanog"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "Nanog"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "Nanog"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "Nanog"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "Nanog"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.