Catalog No: OPPA00704 (Formerly GWB-9ED529)
Size:2UG
Price: $75.00
SKU
OPPA00704
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Myostatin Protein (OPPA00704)

Datasheets/ManualsPrintable datasheet for OPPA00704
Product Info
Predicted Species ReactivityHuman
Product FormatSterile filtered (0.4 um) and lyophilized from 0.5 mg/ml in 0.05M acetate buffer, pH 4.5.
HostE. Coli
ApplicationELISA, WB
Additional InformationSolubility: Add 0.1M Acetate buffer pH-4 to prepare a working stock solution of approximately 0.5 mg/mL and let the lyophilized pellet dissolve completely. For conversion into higher pH value, we recommend intensive dilution by relevant buffer to a concentration of 10ug/ml. In higher concentrations the solubility of this antigen is limited.
::Product Introduction: Myostatin (GDF-8) is expressed uniquely in human skeletal muscle as a 12 kDa mature glycoprotein consisting of 113 amino acid residues and secreted into plasma. Myostatin is a member of the transforming growth factor * superfamily of secreted growth and differentiation factors that is essential for proper regulation of skeletal muscle mass. Studies have shown that myostatin could play an important role in cardiac development and physiology.
Product Description: Total 152AA. M.W. 16.7kDa (calculated). N-terminal His-tag and spacer (43AA - highlighted). The AA sequence of the human myostatin part of the fusion protein is corresponding to the UniProtKB/Swiss-Prot entry O14793.MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDPSSRSAVR SRRDFGLDCD EHSTESRCCR YPLTVDFEAFGWDWIIAPKR YKANYCSGEC EFVFLQKYPH THLVHQANPR GSAGPCCTPT KMSPINMLYF NGKEQIIYGKIPAMVVDRCG CS.
Reconstitution and StorageStore lyophilized protein at -20C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4C for a limited period of time; it does not show any change after two weeks at 4C. The lyophilized GDF-8 remains stable until the expiry date when stored at -20C.
PurityGreater than 95% as determined by SDS-PAGE.
Gene SymbolMyostatin His
Alias SymbolsGDF8, MSLHP
NCBI Gene Id2660
Protein NameGrowth/differentiation factor 8
Description of TargetRecombinant Human Myostatin, His-Tag
Uniprot IDO14793
Protein Accession #NP_005250.1
Protein Size (# AA)Recombinant
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