Myostatin ProPeptide Protein (OPPA00707)

Catalog No: OPPA00707 (Formerly GWB-9A377A)

Size:5UG

Product Info

• Predicted Species Reactivity: Human
• Product Format: Lyophilized from 10mM Acetic Acid. Physical appearance: Sterile Filtered white lyophilized (freeze-dried) powder.
• Reconstitution and Storage: Reconstitution: It is recommended to reconstitute the lyophilized Myostatin Propeptide in sterile 20mM HCl at 0.1 mg/ml, which can then be further diluted to other aqueous solutions.
  Storage: Store lyophilized protein at -20C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4C for a limited period of time.
• Purity: Greater than 95.0% as determined by:
  (a) Analysis by RP-HPLC.
  (b) Analysis by SDS-PAGE.
• Protein Sequence: MNENSEQKE NVEKEGLCNA CTWRQNTKSS RIEAIKIQIL SKLRLETAPN ISKDVIRQLL PKAPPLRELI DQYDVQRDDS SDGSLEDDDY HATTETIITM PTESDFLMQV DGKPKCCFFK FSSKIQYNKV VKAQLWIYLR PVETPTTVFV QILRLIKPMK DGTRYTGIRS LKLDMNPGTG IWQSIDVKTV LQNWLKQPES NLGIEIKALD ENGHDLAVTF PGPGEDGLNP FLEVKVTDTP KRSRR.
• Source: E. coli

Target Info

• Gene Symbol: Myostatin Propetide
• Alias Symbols: GDF8, MSLHP
• NCBI Gene Id: 2660
• Protein Name: Growth/differentiation factor 8
• Description of Target: Myostatin (GDF-8), a member of the TGFbeta superfamily, is a potent and specific negative regulator of skeletal muscle mass. In serum, myostatin circulates as part of a latent complex containing myostatin propeptide and/or follistatin-related gene. The myostatin propeptide is known to bind and inhibit myostatin in vitro. This interaction is relevant in vivo, with a majority (>70%) of myostatin in serum bound to its propeptide. The myostatin propeptide is negative regulator of myostatin in vivo.
• Uniprot ID: O14793
• Protein Accession #: NP_005250.1
• Protein Size (# AA): Recombinant