- Toll Free: 888-880-0001
- Phone: 858-552-6979
- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
| Datasheets/Manuals | Printable datasheet for anti-MYL12A (OASG04561) antibody |
|---|
| Predicted Species Reactivity | Human, Mouse, Rat |
|---|---|
| Product Format | Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Application | IHC |
| Reconstitution and Storage | Store at -20C. Avoid repeated freeze/thaw cycles. |
| Immunogen | Synthesized peptide derived from human MLC-2 around the phosphorylation site of T17/S18. Location: 1-80aa. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Target Post-Translational Modification | Phospho-Thr17/S18 |
| Specificity | Phospho-MLC-2 (T17/S18) Polyclonal Antibody detects endogenous levels of MLC-2 protein only when phosphorylated at T17/S18. |
| Application Info | IHC 1:100-1:300; ELISA 1:10000; |
| Gene Symbol | MYL12A, MYL12B, MYL9 |
|---|---|
| Gene Full Name | myosin, light chain 12A, regulatory, non-sarcomeric |
| Alias Symbols | MLCB, MRCL3, MRLC3, MYL2B, MLC-2B, HEL-S-24 |
| NCBI Gene Id | 10627; 67938; 98932; 50685; 296313 |
| Description of Target | This gene encodes a nonsarcomeric myosin regulatory light chain. This protein is activated by phosphorylation and regulates smooth muscle and non-muscle cell contraction. This protein may also be involved in DNA damage repair by sequestering the transcriptional regulator apoptosis-antagonizing transcription factor (AATF)/Che-1 which functions as a repressor of p53-driven apoptosis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8. |
| Uniprot ID | P19105, O14950, P24844, Q3THE2, Q9CQ19, P18666, Q64122 |
| Molecular Weight | 19794/19779/19827 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
-
See our General FAQ page.
-
What is the species homology for "MYL12A Antibody (Phospho-Thr17/S18) (OASG04561)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".
-
How long will it take to receive "MYL12A Antibody (Phospho-Thr17/S18) (OASG04561)"?
This item is available "Domestic: within 2-3 weeks delivery | International: 2-3 weeks".
-
What buffer format is "MYL12A Antibody (Phospho-Thr17/S18) (OASG04561)" provided in?
This item is provided in "Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "MYL12A Antibody (Phospho-Thr17/S18) (OASG04561)"?
This target may also be called "MLCB, MRCL3, MRLC3, MYL2B, MLC-2B, HEL-S-24" in publications.
-
What is the shipping cost for "MYL12A Antibody (Phospho-Thr17/S18) (OASG04561)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
-
What is the guarantee for "MYL12A Antibody (Phospho-Thr17/S18) (OASG04561)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
-
Can I get bulk pricing for "MYL12A Antibody (Phospho-Thr17/S18) (OASG04561)"?
You can get bulk pricing for this item by going here.
-
What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "19794/19779/19827 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "MYL12A Antibody (Phospho-Thr17/S18) (OASG04561)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
-
What are positive controls for "MYL12A, MYL12B, MYL9"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
-
What are negative controls for "MYL12A, MYL12B, MYL9"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
-
What other proteins interact with "MYL12A, MYL12B, MYL9"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
-
What biological processes are associated with "MYL12A, MYL12B, MYL9"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
-
What cellular components are associated with "MYL12A, MYL12B, MYL9"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
-
What protein functions are associated with "MYL12A, MYL12B, MYL9"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.