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Catalog No: ARP48072_P050
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ARP48072_P050
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Datasheets/ManualsPrintable datasheet for anti-MYH9 (ARP48072_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Dog, Guinea Pig, Pig, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of human MYH9
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceDog: 93%; Guinea Pig: 86%; Human: 100%; Mouse: 86%; Pig: 93%; Rabbit: 86%; Rat: 93%
Peptide SequenceSynthetic peptide located within the following region: DAMNREVSSLKNKLRRGDLPFVVPRRMARKGAGDGSDEEVDGKADGAEAK
Concentration0.5 mg/ml
Blocking PeptideFor anti-MYH9 (ARP48072_P050) antibody is Catalog # AAP48072 (Previous Catalog # AAPP28207)
ReferenceClark,K., (2008) J. Mol. Biol. 378 (4), 788-801
Publications

Dlc1 interaction with non-muscle myosin heavy chain II-A (Myh9) and Rac1 activation. Biol Open. 5, 452-60 (2016). 26977077

Gene SymbolMYH9
Gene Full NameMyosin, heavy chain 9, non-muscle
Alias SymbolsMHA, FTNS, EPSTS, BDPLT6, DFNA17, MATINS, NMMHCA, NMHC-II-A, NMMHC-IIA
NCBI Gene Id4627
Protein NameMyosin-9
Description of TargetMYH9 is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain. The protein is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in MYH9 are the cause of non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness.
Uniprot IDP35579
Protein Accession #NP_002464
Nucleotide Accession #NM_002473
Protein Size (# AA)1960
Molecular Weight226kDa
Protein InteractionsHUWE1; UBC; TP53; SUMO2; SUMO3; IVNS1ABP; LGR4; MDM2; RPA3; RPA2; RPA1; EED; MYL6; MYH14; CDC73; OTUD6B; AKAP10; MYL12A; MYL9; TARDBP; FN1; UBD; PIK3C3; ACE; CSNK2A1; ACTB; PAN2; ITGA4; HSP90AB1; HSP90AA1; ESR1; CASP4; IQCB1; VCAM1; PPP2CA; Fcho2; TRAF3IP
  1. What is the species homology for "MYH9 Antibody - middle region (ARP48072_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Dog, Guinea Pig, Pig, Rabbit".

  2. How long will it take to receive "MYH9 Antibody - middle region (ARP48072_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "MYH9 Antibody - middle region (ARP48072_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "MYH9 Antibody - middle region (ARP48072_P050)"?

    This target may also be called "MHA, FTNS, EPSTS, BDPLT6, DFNA17, MATINS, NMMHCA, NMHC-II-A, NMMHC-IIA" in publications.

  5. What is the shipping cost for "MYH9 Antibody - middle region (ARP48072_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "MYH9 Antibody - middle region (ARP48072_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "MYH9 Antibody - middle region (ARP48072_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "226kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "MYH9 Antibody - middle region (ARP48072_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "MYH9"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "MYH9"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "MYH9"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "MYH9"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "MYH9"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "MYH9"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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