MYD88 Antibody (OAGA04173)

Catalog No: OAGA04173

Size:100 ul

MYD88 antibody detects MYD88 protein by immunofluorescent analysis.
Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 10 min.
Green: MYD88 protein stained by MYD88 antibody diluted at 1:100.
Blue: Hoechst 33342 staining.
Scale bar = 10 um.

ELISA detection of MyD88 using for capture at a concentration of 5 ug/mL and for detection at a concentration of 5 ug/mL.

Product Info

• Product Format: Liquid
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: ICC, IF
• Reconstitution and Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Immunogen: Recombinant protein encompassing a sequence within the center region of human MYD88. The exact sequence is proprietary.
• Purification: Purified by antigen-affinity chromatography.
• Concentration: 0.93 mg/ml
• Preservative: 0.01% Thimerosal
• Application Info: Suggested starting dilutions are as follows: ELISA: 1:1000-1:10000, ICC/IF: 1:100-1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
• Storage Buffer: 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Target Info

• Gene Symbol: MYD88
• Gene Full Name: myeloid differentiation primary response 88
• Alias Symbols: IMD68, MYD88D
• NCBI Gene Id: 4615
• Protein Name: myeloid differentiation primary response protein MyD88
• Description of Target: This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.
• Uniprot ID: Q99836
• Protein Accession #: NP_001166037.1
• Nucleotide Accession #: NM_001172566.1