MYBL2 Antibody (Phospho-Ser577) (OASG00804)

Catalog No: OASG00804

Size:100 uL

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB, IF
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from human B-Myb around the phosphorylation site of S577. Location: 520-600aa.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Target Post-Translational Modification: Phospho-Ser577
• Specificity: Phospho-B-Myb (S577) Polyclonal Antibody detects endogenous levels of B-Myb protein only when phosphorylated at S577.
• Application Info: WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:40000;

Target Info

• Gene Symbol: MYBL2
• Gene Full Name: v-myb avian myeloblastosis viral oncogene homolog-like 2
• Alias Symbols: BMYB, B-MYB
• NCBI Gene Id: 4605; 17865;
• Description of Target: The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene.
• Uniprot ID: P10244, P48972
• Molecular Weight: 80 kDa