Catalog No: ARP58642_P050-HRP
Size:100ul
Price: $434.00
SKU
ARP58642_P050-HRP
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MVP Antibody - N-terminal region : HRP (ARP58642_P050-HRP)

Datasheets/ManualsPrintable datasheet for anti-MVP (ARP58642_P050-HRP) antibody
Product Info
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish
Product FormatLiquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
ClonalityPolyclonal
HostRabbit
ConjugationHRP: Horseradish Peroxidase
ApplicationWB
Reconstitution and StorageAll conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human MVP
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%
Peptide SequenceSynthetic peptide located within the following region: MATEEFIIRIPPYHYIHVLDQNSNVSRVEVGPKTYIRQDNERVLFAPMRM
Concentration0.5 mg/ml
Blocking PeptideFor anti-MVP (ARP58642_P050-HRP) antibody is Catalog # AAP58642 (Previous Catalog # AAPP35779)
Referencede (2008) Cytometry B Clin Cytom 74 (3), 163-168
Gene SymbolMVP
Gene Full NameMajor vault protein
Alias SymbolsLRP, VAULT1
NCBI Gene Id9961
Protein NameMajor vault protein
Description of TargetMVP is required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. MVP down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. MVP down-regulates SRC activity and signaling through MAP kinases.This gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts.
Uniprot IDQ14764
Protein Accession #NP_005106
Nucleotide Accession #NM_005115
Protein Size (# AA)893
Molecular Weight98kDa
Protein InteractionsMVP; SKIL; TRIM27; REL; PLSCR1; MEOX2; MEOX1; MDFI; KPNA3; GOLGA2; DLX2; CAMK2B; AES; TRIP6; TRAF2; TP53; TFCP2; TCF4; SUMO2; NOTCH2NL; CCDC36; TRIM42; FAM154A; PIH1D2; RAB3IP; RIMBP3; C1orf94; RHOXF2; ZMIZ2; OBFC1; RFWD2; MKL1; VAC14; BANP; FAM46C; KCTD9
  1. What is the species homology for "MVP Antibody - N-terminal region : HRP (ARP58642_P050-HRP)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish".

  2. How long will it take to receive "MVP Antibody - N-terminal region : HRP (ARP58642_P050-HRP)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "MVP Antibody - N-terminal region : HRP (ARP58642_P050-HRP)" provided in?

    This item is provided in "Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "MVP Antibody - N-terminal region : HRP (ARP58642_P050-HRP)"?

    This target may also be called "LRP, VAULT1" in publications.

  5. What is the shipping cost for "MVP Antibody - N-terminal region : HRP (ARP58642_P050-HRP)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "MVP Antibody - N-terminal region : HRP (ARP58642_P050-HRP)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "MVP Antibody - N-terminal region : HRP (ARP58642_P050-HRP)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "98kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "MVP Antibody - N-terminal region : HRP (ARP58642_P050-HRP)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "MVP"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "MVP"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "MVP"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "MVP"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "MVP"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "MVP"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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