Muc1 Antibody (OAMA01337)

Catalog No: OAMA01337

Size:1 mg

Product Info

• Product Format: Liquid PBS (pH 7.4) with 0.09% sodium azide
• Clonality: Monoclonal
• Clone: M4H2
• Isotype: IgG
• Host: Mouse
• Application: IHC-F, IHC-P, EIA, Pr
• Reconstitution and Storage: Store at 2 to 8°C.
• Immunogen: Recombinant (E.coli) VNTR20 (tandem repeat in MUC1 core) polypeptide
• Purification: Protein A Chromatography
• Concentration: 7.1 mg/ml (OD280nm, E^0.1%=1.4)
• Specificity: Binds with high efficiency with different epitopes within the VNTR tandem repeat peptide region of MUC1 molecule. Reacts with VNTR20 recombinant unglycosylated fragment of MUC1 protein, with monomeric VNTR MUC1 peptide, with deglycosylated and underglycosylated natural MUC1. Belongs to MAb clusters 6 and 7 according to ISOMB TD-4 classification. Non cross reactive with normal serum proteins and human tissues of nonepithelial origin.
• Source: Ascites
• Purity: >90% pure (SDS-PAGE)
• Application Info: Suitable for use in Immunohistochemical and Immunofluorescent detection of neoplastic breast epithelium, and breast, lung and ovarian tumor tissues (frozen and paraffin) MUC1 are abundantly present on the surface of growing tumor cell lines and on the surface and cytoplasm of malignant cells of epithelial origin. May be used development of highly effective ELISA tests for unglycosylated and underglycosylated tumor associated MUC1 mucins in human serum. May also be used for the solid-phase capture of MUC1 isoforms.

Target Info

• Alias Symbols: EMA, MCD, PEM, PUM, KL-6, MAM6, MCKD, PEMT, CD227, H23AG, MCKD1, MUC-1, ADMCKD, ADTKD2, ADMCKD1, CA 15-3, MUC-1/X, MUC1/ZD, MUC-1/SEC
• NCBI Gene Id: 4582
• Protein Name: Mucin-1
• Uniprot ID: P15941
• Protein Accession #: NP_001018016.1