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MUC1 Antibody (OAGA01293)

100 ul
$329.00
In Stock
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Predicted Species Reactivity:
Human
Product Format:
Liquid. 1XPBS, 1%BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Clonality:
Polyclonal
Isotype:
IgG
Host:
Rabbit
Application:
IF, IHC-P, IP, WB
Reconstitution and Storage:
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Gene Symbol:
MUC1
Official Gene Full Name:
mucin 1, cell surface associated
NCBI Gene Id:
4582
Swissprot Id:
P15941
Alias Symbols:
EMA, MCD, PEM, PUM, KL-6, MAM6, MCKD, PEMT, CD227, H23AG, MCKD1, MUC-1, ADMCKD, ADMCKD1, CA 15-3, MUC-1/X, MUC1/ZD, MUC-1/SEC
Replacement Item:
This antibody may replace item sc-15333, HPA008855
Description of Target:
This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.
Purification:
Purified by antigen-affinity chromatography.
Tissue Tool:
Find tissues and cell lines supported to express MUC1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express MUC1.
Immunogen:
Recombinant protein encompassing a sequence within the center region of human MUC1. The exact sequence is proprietary.
Concentration:
1mg/ml
Datasheets/Manuals:
Printable datasheet for anti-MUC1 (OAGA01293) antibody
Application Info:
Suggested starting dilutions are as follows: WB: 1:1000-1:10000, IHC-P: 1:100-1:1000, ICC/IF: 1:100-1:1000, IP: 1:100-1:500. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

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