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MUC1 Antibody - C-terminal region (ARP41446_T100)

100 ul
$249.00
In Stock
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Conjugation Options

ARP41446_T100-FITC Conjugated

ARP41446_T100-HRP Conjugated

ARP41446_T100-Biotin Conjugated

Tested Species Reactivity:
Human, Pig
Predicted Species Reactivity:
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality:
Polyclonal
Host:
Rabbit
Application:
IHC, WB
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Gene Symbol:
MUC1
Official Gene Full Name:
Mucin 1, cell surface associated
NCBI Gene Id:
4582
Protein Name:
Mucin-1
Swissprot Id:
Q7Z552
Protein Accession #:
NP_001037855
Nucleotide Accession #:
NM_001044390
Alias Symbols:
CD227, EMA, PEM, PUM, mucin, KL-6, MAM6, PEMT, H23AG, MUC-1, MUC-1/X, MUC1/ZD, MUC-1/SEC
Replacement Item:
This antibody may replace item sc-15333, HPA008855
Description of Target:
MUC1 is a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas.
Protein Size (# AA):
203
Molecular Weight:
22kDa
Purification:
Protein A purified
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express MUC1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express MUC1.
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human MUC1
Predicted Homology Based on Immunogen Sequence:
Cow: 86%; Dog: 100%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 86%; Rabbit: 92%; Rat: 92%
Complete computational species homology data:
Anti-MUC1 (ARP41446_T100)
Peptide Sequence:
Synthetic peptide located within the following region: RRKNYGQLDIFPARDTYHPMSEYPTYHTHGRYVPPSSTDRSPYEKVSAGN
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
UBC; PPARG; IPO5; NUP62; EGFR; ABL1; SRC; JUN; TP53; TBP; IKBKG; TNFRSF1A; IKBKB; GRB2; ESR1; GALNT15; GALNT12; GALNT10; OSGEP; GSK3B; GALNT2; GALNT1; CTNND1; SIGLEC1; ERBB4; ERBB3; SOS1; PRKCD; ZAP70; APC; JUP; LYN; ERBB2; LCK; CTNNB1; GALNT4; BAX; CDKN1
Blocking Peptide:
For anti-MUC1 (ARP41446_T100) antibody is Catalog # AAP41446 (Previous Catalog # AAPP24183)
Datasheets/Manuals:
Printable datasheet for anti-MUC1 (ARP41446_T100) antibody
Publications:

Braun, HS; Sponder, G; Pieper, R; Aschenbach, JR; Deiner, C; GABA selectively increases mucin-1 expression in isolated pig jejunum. 10, 47 (2015). IHC, WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat 26471792

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