MTNR1B Antibody - N-terminal region : FITC (ARP64072_P050-FITC)

Catalog No: ARP64072_P050-FITC

Size:100ul

Product Info

• Predicted Species Reactivity: Human, Pig, Rabbit
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: FITC: Fluorescein Isothiocyanate
• Application: WB
• Reconstitution and Storage: All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Human: 100%; Pig: 79%; Rabbit: 79%
• Peptide Sequence: Synthetic peptide located within the following region: SFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDV
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-MTNR1B (ARP64072_P050-FITC) antibody is Catalog # AAP64072
• Publications:

  Santoro, R. et al. Blockage of melatonin receptors impairs p53-mediated prevention of DNA damage accumulation. Carcinogenesis 34, 1051-61 (2013). WB, Human, Pig, Rabbit 23354312

Target Info

• Gene Symbol: MTNR1B
• Gene Full Name: Melatonin receptor 1B
• Alias Symbols: MT2, FGQTL2, MEL-1B-R
• NCBI Gene Id: 4544
• Protein Name: Melatonin receptor type 1B
• Description of Target: This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin.
• Uniprot ID: P49286
• Protein Accession #: NP_005950
• Nucleotide Accession #: NM_005959
• Protein Size (# AA): 362
• Molecular Weight: 40kDa
• Protein Interactions: GNAI1; GPR50; ITM2C; HNRNPA0; GNB4; PPM1G; PI4KA; PDIA6; VPS35; IRS4; COPA; CTNND1; MTNR1B; MTNR1A; FLNA; YWHAQ; GNB1; GNAI3; GNAI2; HSPA5; CANX;