Size:100 ul
$319.00
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SKU
ARP64072_P050
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Conjugation Options

ARP64072_P050-FITC Conjugated

ARP64072_P050-HRP Conjugated

ARP64072_P050-Biotin Conjugated

MTNR1B Antibody - N-terminal region (ARP64072_P050)

Catalog#: ARP64072_P050
Domestic: within 1-2 days delivery | International: 1-2 days
More Information
Tested Species Reactivity Human
Predicted Species Reactivity Human, Pig, Rabbit
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality Polyclonal
Host Rabbit
Application WB
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-13174 from Santa Cruz Biotechnology.
Purification Affinity Purified
Predicted Homology Based on Immunogen Sequence Human: 100%; Pig: 79%; Rabbit: 79%
Complete computational species homology data Anti-MTNR1B (ARP64072_P050)
Peptide Sequence Synthetic peptide located within the following region: SFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDV
Concentration Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide For anti-MTNR1B (ARP64072_P050) antibody is Catalog # AAP64072
Datasheets/Manuals Printable datasheet for anti-MTNR1B (ARP64072_P050) antibody
Publications

Santoro, R. et al. Blockage of melatonin receptors impairs p53-mediated prevention of DNA damage accumulation. Carcinogenesis 34, 1051-61 (2013). WB, Human, Pig, Rabbit 23354312

Gene Symbol MTNR1B
Official Gene Full Name Melatonin receptor 1B
Alias Symbols FGQTL2, MEL-1B-R, MT2
NCBI Gene Id 4544
Protein Name Melatonin receptor type 1B
Description of Target This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin.
Swissprot Id P49286
Protein Accession # NP_005950
Nucleotide Accession # NM_005959
Protein Size (# AA) 362
Molecular Weight 40kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express MTNR1B.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express MTNR1B.
Protein Interactions GNAI1; GPR50; ITM2C; HNRNPA0; GNB4; PPM1G; PI4KA; PDIA6; VPS35; IRS4; COPA; CTNND1; MTNR1B; MTNR1A; FLNA; YWHAQ; GNB1; GNAI3; GNAI2; HSPA5; CANX;
  1. What is the species homology for "MTNR1B Antibody - N-terminal region (ARP64072_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Pig, Rabbit".

  2. How long will it take to receive "MTNR1B Antibody - N-terminal region (ARP64072_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "MTNR1B Antibody - N-terminal region (ARP64072_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "MTNR1B Antibody - N-terminal region (ARP64072_P050)"?

    This target may also be called "FGQTL2, MEL-1B-R, MT2" in publications.

  5. What is the shipping cost for "MTNR1B Antibody - N-terminal region (ARP64072_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "MTNR1B Antibody - N-terminal region (ARP64072_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "MTNR1B Antibody - N-terminal region (ARP64072_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "40kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "MTNR1B Antibody - N-terminal region (ARP64072_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "MTNR1B"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "MTNR1B"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "MTNR1B"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "MTNR1B"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "MTNR1B"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "MTNR1B"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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