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Datasheets/Manuals | Printable datasheet for MTBP Antibody (OAPB00140) (OAPB00140) |
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Predicted Species Reactivity | Human|Mouse |
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Product Format | Liquid. MTBP Antibody is supplied in PBS containing 0.02% sodium azide. |
Clonality | Polyclonal |
Host | Rabbit |
Conjugation | Unconjugated |
Application | Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Western blot |
:: | Buffer: Antibody is supplied in PBS containing 0.02% sodium azide. |
Reconstitution and Storage | MTBP antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Immunogen | MTBP antibody was raised against a 18 amino acid peptide near the center of human MTBP. The immunogen is located within amino acids 110 - 160 of MTBP. |
Purification | Affinity Purified |
Predicted Homology Based on Immunogen Sequence | Human |
Concentration | 1 mg/ml |
Blocking Peptide | For anti-MTBP (OAPB00140) antibody is Catalog # OEPB02252 |
Application Info | MTBP antibody can be used for detection of MTBP by Western blot at 0.5 to 1 ug/ml. K562 cell lysate can be used as positive control and a 104 kDa band can be detected. (Optimal dilution should be determined by user) |
Reference | Matsuoka S, Huang M, Elledge SJ. Linkage of ATM to cell cycle regulation by the Chk2 protein kinase. Science. 1998;282:1893-7. ;Tanaka H, Arakawa H, Yamaguchi T, Shiraishi K, Fukuda S, Matsui K, Takei Y, Nakamura Y. A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage. Nature. 2000;404:42-9. ;Oda E, Ohki R, Murasawa H, Nemoto J, Shibue T, Yamashita T, Tokino T, Taniguchi T, Tanaka N. Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. Science. 2000;288(5468):1053-8.;Oda K, Arakawa H, Tanaka T, Matsuda K, Tanikawa C, Mori T, Nishimori H, Tamai K, Tokino T, Nakamura Y, Taya Y. p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53. Cell. 2000 Sep 15;102(6):849-62. |
Gene Symbol | MTBP |
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Gene Full Name | MDM2 binding protein |
Alias Symbols | MDM2 (mouse double minute 2)-binding protein, 104kD;Mdm2, transformed 3T3 cell double minute 2, p53 binding protein binding protein, 104kDa;mdm2-binding protein;MDM2BP. |
NCBI Gene Id | 27085 |
Protein Name | Mdm2-binding protein|mdm2-binding protein [Homo sapiens] |
Description of Target | Inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells (By similarity). May play a role in MDM2-dependent p53/TP53 homeostasis in unstressed cells. Inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of p53/TP53 and its subsequent degradation. |
Uniprot ID | Q96DY7 |
Protein Accession # | https://www.ncbi.nlm.nih.gov/protein/NP_071328 |
Nucleotide Accession # | NM_022045.4 |
Molecular Weight | Predicted: 104 kDa Observed: 104 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "MTBP Antibody (OAPB00140)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse".
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How long will it take to receive "MTBP Antibody (OAPB00140)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
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What buffer format is "MTBP Antibody (OAPB00140)" provided in?
This item is provided in "Liquid. MTBP Antibody is supplied in PBS containing 0.02% sodium azide.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "MTBP Antibody (OAPB00140)"?
This target may also be called "MDM2 (mouse double minute 2)-binding protein, 104kD;Mdm2, transformed 3T3 cell double minute 2, p53 binding protein binding protein, 104kDa;mdm2-binding protein;MDM2BP." in publications.
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What is the shipping cost for "MTBP Antibody (OAPB00140)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "MTBP Antibody (OAPB00140)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "MTBP Antibody (OAPB00140)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "Predicted: 104 kDa Observed: 104 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "MTBP Antibody (OAPB00140)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "MTBP"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "MTBP"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "MTBP"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "MTBP"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "MTBP"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "MTBP"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.