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MTAP Antibody (OAGA00741)

100 ul
$409.00
In Stock
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Predicted Species Reactivity:
Human, Mouse
Product Format:
Liquid
Clonality:
Polyclonal
Isotype:
IgG
Host:
Rabbit
Application:
IHC-FFPE, WB
Additional Information:
Background: This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown. [provided by RefSeq]
:::
Positive Controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji, mouse liver
:::
Cellular Localization: Cytoplasm
Reconstitution and Storage:
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Gene Symbol:
MTAP
Official Gene Full Name:
S-methyl-5'-thioadenosine phosphorylase
NCBI Gene Id:
4507
Protein Name:
S-methyl-5'-thioadenosine phosphorylase
Swissprot Id:
Q13126
Protein Accession #:
NP_002442.2
Alias Symbols:
MSAP antibody, c86fus antibody, MTAP antibody, MTA phosphorylase antibody, S-methyl-5'-thioadenosine phosphorylase antibody, 5'-methylthioadenosine phosphorylase antibody, MeSAdo phosphorylase antibody, MTAPase antibody, methylthioadenosine phosphorylase
Replacement Item:
This antibody may replace item sc-100782 from Santa Cruz Biotechnology.
Molecular Weight:
31 kDa
Purification:
Purified by antigen-affinity chromatography.
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express MTAP.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express MTAP.
Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 283 of MTAP (Uniprot ID#Q13126)
Concentration:
1 mg/ml
Datasheets/Manuals:
Printable datasheet for anti-MTAP antibody - OAGA00741
Application Info:
Suggested starting dilutions are as follows: WB: 1:500-1:3000, IHC-P: 1:100-1:1000 [suggested antigen retrieval using heat mediated 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0)]. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Storage Buffer:
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

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