MSLN Antibody (OAGA00400)

Catalog No: OAGA00400

Size:100 ul

Sample(30 ?g of whole cell lysate)
A:293T
7.5% SDS PAGE
OAGA00400 diluted at 1:1000

Immunohistochemical analysis of paraffin-embedded serous OVCA, using MSLN(OAGA00400) antibody at 1:100 dilution.

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid. 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB, IHC-P
• Additional Information: Positive Control: 293T
  Cellular Localization: Cell membrane; Lipid-anchor , GPI-anchor , Golgi apparatus , Megakaryocyte-potentiating factor: Secreted , Isoform 3: Secreted
• Reconstitution and Storage: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
• Immunogen: Recombinant protein encompassing a sequence within the center region of human Mesothelin. The exact sequence is proprietary.
• Purification: Purified by antigen-affinity chromatography.
• Concentration: 1 mg/ml
• Application Info: WB: 1:500-1:3000
  IHC-P: 1:100-1:1000
  Optimal dilutions should be determined by the end user.

Target Info

• Gene Symbol: MSLN
• Gene Full Name: Mesothelin
• Alias Symbols: MPF, SMRP
• NCBI Gene Id: 10232
• Protein Name: Mesothelin
• Description of Target: An antibody that reacts with ovarian cancers and mesotheliomas was used to isolate a cell surface antigen named mesothelin. Although the function of mesothelin is unknown, it may play a role in cellular adhesion and is present on mesothelium, mesotheliomas, and ovarian cancers. This gene encodes a preproprotein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Alternative splicing results in multiple transcript variants.
• Uniprot ID: Q13421
• Protein Accession #: NP_001170826.1
• Molecular Weight: 69 kDa