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MSI2 Antibody - N-terminal region (ARP41110_P050)

100 ul
$289.00
In Stock
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Conjugation Options

ARP41110_P050-FITC Conjugated

ARP41110_P050-HRP Conjugated

ARP41110_P050-Biotin Conjugated

Gene Symbol:
MSI2
Official Gene Full Name:
Musashi homolog 2 (Drosophila)
NCBI Gene Id:
124540
Protein Name:
RNA-binding protein Musashi homolog 2
Swissprot Id:
Q96DH6
Protein Accession #:
NP_620412
Nucleotide Accession #:
NM_138962
Alias Symbols:
FLJ36569, MGC3245, MSI2H
Replacement Item:
This antibody may replace item sc-367844 from Santa Cruz Biotechnology.
Description of Target:
MSI2 contains two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Two transcript variants encoding distinct isoforms have been identified for this gene.
Protein Size (# AA):
328
Molecular Weight:
35kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express MSI2.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express MSI2.
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human MSI2
Predicted Species Reactivity:
Human, Mouse, Pig, Rabbit, Rat, Zebrafish
Tested Species Reactivity:
Human
Predicted Homology Based on Immunogen Sequence:
Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Complete computational species homology data:
Anti-MSI2 (ARP41110_P050)
Peptide Sequence:
Synthetic peptide located within the following region: EANGSQGTSGSANDSQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECM
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
MEOX2; HNRNPH2; SUMO2; RPA3; RPA2; RPA1; SUZ12; RNF2; BMI1; TARDBP; SOX2; VCAM1; UBC; CUL3; H2AFX; GRB2;
Blocking Peptide:
For anti-MSI2 (ARP41110_P050) antibody is Catalog # AAP41110 (Previous Catalog # AAPS02408)
Datasheets/Manuals:
Printable datasheet for anti-MSI2 (ARP41110_P050) antibody
Target Reference:
Barbouti,A., (2003) Cancer Res. 63 (6), 1202-1206
Publications:

Cox, J. L. et al. The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells. PLoS One 8, e62857 (2013). WB, Human, Mouse, Pig, Rabbit, Rat, Zebrafish 23667531

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