- Toll Free: 888-880-0001
- Phone: 858-552-6979
- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
| Datasheets/Manuals | Printable datasheet for OAAF08321 |
|---|
| Tested Species Reactivity | Human |
|---|---|
| Product Format | Liquid. Supplied in 1% BSA, 0.05M Tris-HCl, 0.15M NaCl, 0.2% Kathon CG/ICP, 0.1% Tween-20 |
| Clonality | Monoclonal |
| Clone | ABT-MSH6 |
| Isotype | IgG |
| Host | Mouse |
| Application | WB, IHC-P |
| Additional Information | Retrieval buffer: TRIS-EDTA of pH8.0 |
| :: | Description: Mouse monoclonal to MutS Protein Homolog 6 (MSH6) |
| Reconstitution and Storage | Shipped at 4C. Store at -20C. Stable for 12 months at -20C. |
| Immunogen | The antiserum was produced against synthesized peptide derived between 940-980 aa of human MSH6. The exact sequence is proprietary. |
| Purification | Immunogen affinity purified |
| Specificity | Anti-MutS Protein Homolog 6 (MSH6) [ABT-MSH6] detects endogenous levels of total MutS Protein Homolog 6 (MSH6) protein. |
| Application Info | IHC 1:200 - 1:400, WB 1:100 - 1:500 |
| Gene Symbol | MSH6 |
|---|---|
| Gene Full Name | mutS homolog 6 |
| Alias Symbols | GTBP, HSAP, p160, GTMBP, HNPCC5, MMRCS3 |
| NCBI Gene Id | 2956 |
| Protein Name | DNA mismatch repair protein Msh6 |
| Description of Target | This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. |
| Uniprot ID | P52701 |
| Protein Accession # | NP_000170.1 |
| Nucleotide Accession # | NM_000179.2 |
| Molecular Weight | 153 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
-
See our General FAQ page.
-
What is the species homology for "MSH6 Antibody (OAAF08321)"?
The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "".
-
How long will it take to receive "MSH6 Antibody (OAAF08321)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".
-
What buffer format is "MSH6 Antibody (OAAF08321)" provided in?
This item is provided in "Liquid. Supplied in 1% BSA, 0.05M Tris-HCl, 0.15M NaCl, 0.2% Kathon CG/ICP, 0.1% Tween-20".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "MSH6 Antibody (OAAF08321)"?
This target may also be called "GTBP, HSAP, p160, GTMBP, HNPCC5, MMRCS3" in publications.
-
What is the shipping cost for "MSH6 Antibody (OAAF08321)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
-
What is the guarantee for "MSH6 Antibody (OAAF08321)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
-
Can I get bulk pricing for "MSH6 Antibody (OAAF08321)"?
You can get bulk pricing for this item by going here.
-
What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "153 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "MSH6 Antibody (OAAF08321)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
-
What are positive controls for "MSH6"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
-
What are negative controls for "MSH6"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
-
What other proteins interact with "MSH6"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
-
What biological processes are associated with "MSH6"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
-
What cellular components are associated with "MSH6"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
-
What protein functions are associated with "MSH6"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
