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Datasheets/Manuals | Printable datasheet for MSH2 Antibody (OAAD00412) - OAAD00412 |
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Predicted Species Reactivity | Human |
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Clonality | Monoclonal |
Clone | 3A2B8C |
Isotype | IgG1 |
Host | Mouse |
Application | WB, IHC |
Formulation | Antibodies are purified by protein G affinity chromatography. |
Application Info | Western Blot: Dilution 1: 200- 1: 1, 000 IHC(P): Dilution 1: 200- 1: 1, 000 IHC(F): Dilution 1: 200- 1: 1, 000 ELISA: Propose dilution 1: 10, 000. Determining optimal working dilutions by titration test. |
Reference | 1.Papadopoulos, N. 1994. Science 263: 1625-1629. 2.Palombo, F. 1994. Nature 367:417-418. |
Gene Symbol | tin |
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Alias Symbols | CG7895, Dmel\CG7895, DmNK-4, DROHOXHK4, DROHOXNK4, HOX, msh-2, msh2, NK-4, NK-4/msh-2, NK4, NK4/msh-2, NKX2.5, Tin, TIN, tin/NK4 |
NCBI Gene Id | 42536 |
Protein Name | Muscle-specific homeobox protein tinman |
Description of Target | MSH2 is a 100 kDa nuclear antigen and encodes a protein of 934 amino acids. The MSH2 gene is one of 4 known genes encoding proteins involved in the repair of mismatch nucleotides following DNA replication or repair. Mutations in the MSH2 gene contribute to the development of sporadic colorectal carcinoma. MSHS mutations are responsible for 50% of inherited non-polyposis colorectal (HNPCC). The repair of mismatch DNA is essential to maintaining the integrity of genetic information over time. An alteration of microsatellite repeats is the result of slippage owing to strand misalignment during DNA replication and is referred to as microsatellite instability (MSI). These defects in DNA repair pathways have been related to human carcinogenesis. MSH-2 is involved in the initial cognition of mismatch nucleotides during the replication mismatch repair process. |
Uniprot ID | P22711 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "MSH2 Antibody (OAAD00412)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "MSH2 Antibody (OAAD00412)"?
This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".
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What buffer format is "MSH2 Antibody (OAAD00412)" provided in?
This item is provided in "".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "MSH2 Antibody (OAAD00412)"?
This target may also be called "CG7895, Dmel\CG7895, DmNK-4, DROHOXHK4, DROHOXNK4, HOX, msh-2, msh2, NK-4, NK-4/msh-2, NK4, NK4/msh-2, NKX2.5, Tin, TIN, tin/NK4" in publications.
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What is the shipping cost for "MSH2 Antibody (OAAD00412)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "MSH2 Antibody (OAAD00412)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "MSH2 Antibody (OAAD00412)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "MSH2 Antibody (OAAD00412)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "TIN"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "TIN"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "TIN"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "TIN"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "TIN"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "TIN"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.