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Catalog No: OAAB19726
Size:100ul
Price: $438.00
SKU
OAAB19726
Availability: Domestic: within 1-2 week delivery | International: within 1-2 week delivery
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for anti-MRE11A (OAAB19726) antibody
Product Info
Predicted Species ReactivityHuman, Mouse, Rat
Product Format0.01M PBS, pH 7.2, 0.1% Sodium azide, Glycerol 50%
ClonalityPolyclonal
HostRabbit
ApplicationWB, IP, ICC, IHC-P
Reconstitution and StorageMaintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Application InfoWB: 1:1000
ReferencePetrini J.H.J.,et al.Genomics 29:80-86(1995).
Petrini J.H.J.,et al.Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases.
Chamankhah M.,et al.Submitted (SEP-1997) to the EMBL/GenBank/DDBJ databases.
Paull T.T.,et al.Mol. Cell 1:969-979(1998).
Pitts S.A.,et al.Hum. Mol. Genet. 10:1155-1162(2001).
Gene SymbolMRE11A
Alias SymbolsATLD, HNGS1, MRE11A, MRE11B
NCBI Gene Id4361
Description of TargetComponent of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-strand endonuclease activity and double-strand- specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity. This could facilitate searches for short or long regions of sequence homology in the recombining DNA templates, and may also stimulate the activity of DNA ligases and/or restrict the nuclease activity of MRE11A to prevent nucleolytic degradation past a given point. The complex may also be required for DNA damage signaling via activation of the ATM kinase. In telomeres the MRN complex may modulate t-loop formation.
Uniprot IDP49959
Molecular Weight81 kDa
  1. What is the species homology for "MRE11A Antibody (OAAB19726)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".

  2. How long will it take to receive "MRE11A Antibody (OAAB19726)"?

    This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".

  3. What buffer format is "MRE11A Antibody (OAAB19726)" provided in?

    This item is provided in "0.01M PBS, pH 7.2, 0.1% Sodium azide, Glycerol 50%".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "MRE11A Antibody (OAAB19726)"?

    This target may also be called "ATLD, HNGS1, MRE11A, MRE11B" in publications.

  5. What is the shipping cost for "MRE11A Antibody (OAAB19726)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "MRE11A Antibody (OAAB19726)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "MRE11A Antibody (OAAB19726)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "81 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "MRE11A Antibody (OAAB19726)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "MRE11A"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "MRE11A"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "MRE11A"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "MRE11A"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "MRE11A"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "MRE11A"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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