MRC1 Recombinant Protein (Human) (OPCA02729)

Catalog No: OPCA02729

Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. Acts as phagocytic receptor for bacteria, fungi and other pathogens.

MRC1 Recombinant Protein (Human) (OPCA02729) in SDS-PAGE showing the molecular weight of approximately 66.38 kDa.

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Liquid or Lyophilized powder
• Host: Human
• Reconstitution and Storage: -20°C or -80°C
• Purification: Affinity purified using IMAC
• Purity: Greater than 90% as determined by SDS-PAGE.
• Peptide Sequence: RTSLCFKLYAKGKHEKKTWFESRDFCRALGGDLASINNKEEQQTIWRLITASGSYHKLFWLGLTYGSPSEGFTWSDGSPVSYENWAYGEPNNYQNVEYCGELKGDPTMSWNDINCEHLNNWICQIQKGQTPKPEPTPAPQDNPPVTEDGWVIYKDYQYYFSKEKETMDNARAFCKRNFGDLVSIQSESEKKFLWKYVNRNDAQSAYFIGLLISLDKKFAWMDGSKVDYVSWATGEPNFANEDENCVTMYSNSGFWNDINCGYPNAFICQRHNSSINATTVMPTMPSVPSGCKEGWNFYSNKCFKIFGFMEEERKNWQEARKACIGFGGNLVSIQNEKEQAFLTYHMKDSTFSAWTGLNDVNSEHTFLWTDGRGVHYTNWGKGYPGGRRSSLSYEDADCVVIIGGASNEAGKWMDDTCDSKRGYICQTRSDPSLTNPPATIQTDGFVKYGKSSYSLMRQKFQWHEAETYCKLHNSLIASILDPYSNAFAWLQMETSNERVWIALNSNLTDNQYTWTDKWRVRYTNWAADEPKLKSACVYLDLDGYWKTAHCNESFYFLCK
• Protein Sequence: Partial Protein: RTSLCFKLYAKGKHEKKTWFESRDFCRALGGDLASINNKEEQQTIWRLITASGSYHKLFWLGLTYGSPSEGFTWSDGSPVSYENWAYGEPNNYQNVEYCGELKGDPTMSWNDINCEHLNNWICQIQKGQTPKPEPTPAPQDNPPVTEDGWVIYKDYQYYFSKEKETMDNARAFCKRNFGDLVSIQSESEKKFLWKYVNRNDAQSAYFIGLLISLDKKFAWMDGSKVDYVSWATGEPNFANEDENCVTMYSNSGFWNDINCGYPNAFICQRHNSSINATTVMPTMPSVPSGCKEGWNFYSNKCFKIFGFMEEERKNWQEARKACIGFGGNLVSIQNEKEQAFLTYHMKDSTFSAWTGLNDVNSEHTFLWTDGRGVHYTNWGKGYPGGRRSSLSYEDADCVVIIGGASNEAGKWMDDTCDSKRGYICQTRSDPSLTNPPATIQTDGFVKYGKSSYSLMRQKFQWHEAETYCKLHNSLIASILDPYSNAFAWLQMETSNERVWIALNSNLTDNQYTWTDKWRVRYTNWAADEPKLKSACVYLDLDGYWKTAHCNESFYFLCK
• Source: Yeast
• Protein Range: 655-1213 aa
• Tag: N-terminal 6xHis-tagged

Target Info

• Reference: Primary structure of the mannose receptor contains multiple motifs resembling carbohydrate-recognition domains.Taylor M.E., Conary J.T., Lennartz M.R., Stahl P.D., Drickamer K.J. Biol. Chem. 265:12156-12162(1990)
• Gene Symbol: MRC1
• Gene Full Name: mannose receptor C-type 1
• Alias Symbols: bA541I19.1;CD206;CLEC13D;CLEC13DL;C-type lectin domain family 13 member D;C-type lectin domain family 13 member D-like;hMR;human mannose receptor;macrophage mannose receptor 1;macrophage mannose receptor 1-like protein 1;mannose receptor, C type 1-like 1;MMR;MRC1L1.
• NCBI Gene Id: 4360
• Protein Name: Macrophage mannose receptor 1
• Description of Target: Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains.
• Uniprot ID: P22897
• Protein Accession #: NP_002429.1
  
• Nucleotide Accession #: NM_002438.3
• Protein Size (# AA): Recombinant
• Molecular Weight: 66.4 kDa