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MRC1 Antibody (OAAB21894)

Catalog#: OAAB21894
More Information
Predicted Species Reactivity Human, Mouse
Product Format Liquid
Clonality Polyclonal
Host Rabbit
Application WB, IF, IHC-P
Additional Information Function: Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. Acts as phagocytic receptor for bacteria, fungi and other pathogens.
Reconstitution and Storage Store at 2-8C for up to 6 months. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-34577, HPA004114
Predicted Homology Based on Immunogen Sequence Human, Mouse
Datasheets/Manuals Printable datasheet for anti-MRC1 (OAAB21894) antibody
Preservative 0.03% Proclin300 and 50% glycerol
Formulation 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Gene Symbol MRC1
Official Gene Full Name mannose receptor, C type 1
Alias Symbols MMR, hMR, CD206, MRC1L1, CLEC13D, CLEC13DL, bA541I19.1
NCBI Gene Id 4360
Description of Target The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.
Swissprot Id P22897
Protein Accession # NP_002429.1
Nucleotide Accession # NM_002438.3
Molecular Weight 166 kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express MRC1.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express MRC1.
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