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MPST Antibody - middle region (ARP48394_P050)

100 ul
$319.00
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Conjugation Options

ARP48394_P050-FITC Conjugated

ARP48394_P050-HRP Conjugated

ARP48394_P050-Biotin Conjugated

Tested Species Reactivity:
Human
Predicted Species Reactivity:
Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality:
Polyclonal
Host:
Rabbit
Application:
WB
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Gene Symbol:
MPST
Official Gene Full Name:
Mercaptopyruvate sulfurtransferase
NCBI Gene Id:
4357
Protein Name:
3-mercaptopyruvate sulfurtransferase
Swissprot Id:
P25325
Protein Accession #:
NP_066949
Nucleotide Accession #:
NM_021126
Alias Symbols:
MGC24539, MST, TST2
Replacement Item:
This antibody may replace item sc-292174 from Santa Cruz Biotechnology.
Description of Target:
MPST transfer of a sulfur ion to cyanide or to other thiol compounds. MPST also has weak rhodanese activity. MPST may have a role in cyanide degradation or in thiosulfate biosynthesis.This gene encodes a protein which can function as a monomer or as a disulfide-linked homodimer and which catalyzes the transfer of a sulfur ion from 3-mercaptopyruvate to cyanide or other thiol compounds. It may be involved in cyanide degradation and in thiosulfate biosynthesis. The encoded cytoplasmic protein is a member of the rhodanese family but is not rhodanese itself, which is a mitochondrial protein. Alternatively spliced transcript variants encoding the same protein have been identified.
Protein Size (# AA):
297
Molecular Weight:
33kDa
Purification:
Affinity Purified
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express MPST.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express MPST.
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human MPST
Predicted Homology Based on Immunogen Sequence:
Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 93%
Complete computational species homology data:
Anti-MPST (ARP48394_P050)
Peptide Sequence:
Synthetic peptide located within the following region: DPAFIKTYEDIKENLESRRFQVVDSRATGRFRGTEPEPRDGIEPGHIPGT
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
UBC; NEDD8; TMEM189; S100A16; NADK2; SEPT11; TIMM9; YKT6; SEC22B; VAPB; UQCRFS1; UPP1; TPI1; NDUFV1; ANXA4; RAE1;
Blocking Peptide:
For anti-MPST (ARP48394_P050) antibody is Catalog # AAP48394 (Previous Catalog # AAPP35724)
Datasheets/Manuals:
Printable datasheet for anti-MPST (ARP48394_P050) antibody
Sample Type Confirmation:

MPST is supported by BioGPS gene expression data to be expressed in HepG2

Target Reference:
Huang,S.H., (2006) Toxicol. Lett. 165 (2), 101-111
Publications:

Cui, X; Navneet, S; Wang, J; Roon, P; Chen, W; Xian, M; Smith, SB; Analysis of MTHFR, CBS, Glutathione, Taurine, and Hydrogen Sulfide Levels in Retinas of Hyperhomocysteinemic Mice. 58, 1954-1963 (2017). WB, Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat 28384716

Otani, S; Nagaoka, T; Omae, T; Tanano, I; Kamiya, T; Ono, S; Hein, TW; Kuo, L; Yoshida, A; Histamine-Induced Dilation of Isolated Porcine Retinal Arterioles: Role of Endothelium-Derived Hyperpolarizing Factor. 57, 4791-8 (2016). WB, Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat 27618417

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