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Catalog No: OOPA00091 (Formerly GWB-BSP245)
Size:5UG
Price: $75.00
SKU
OOPA00091
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MPO Human - Human Myeloperoxidase (OOPA00091)

Datasheets/ManualsPrintable datasheet for OOPA00091
Product Info
HostNative.
::Product Introduction: Myeloperoxidase is an important enzyme used by granulocytes during phagocytic lysis of foreign particles engulfed. In normal tissues and in a variety of myeloproliferative disorders myeloid cells of both neutrophilic and eosinophilic types, at all stages of maturation, exhibit strong cytoplasmic reactivity for MPO. Erythroid precursors, megakaryocytes, lymphoid cells, mast cells, and plasma cells are nonreactive. MPO is not observed in the neoplastic cells of a wide variety of epithelial tumors and sarcomas. MPO is useful in differentiating between myeloid and lymphoid leukemias.
Product Description: MPO is a natural protein having a molecular mass of 150kDa containing 2 subunits each of a heavy chain with 64kDa and a light chain with 13kDa. MPO is isolated from human peripheral blood polymorphonuclear leukocytes.
PurityGreater than 80% as determined by SDS-PAGE.
Application InfoWestern blot with rabbit anti-MPO antisera and green color indicates presence of "green heme" cofactor.
FormulationMPO is supplied in 16mM HEPES buffer pH-8.0, 400mM NaCl, and 20% glycerol.
PurificationGreater than 80% as determined by SDS-PAGE.
Gene SymbolMPO
Alias SymbolsMyeloperoxidase, EC 1.11.1.7, MPO.
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