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Datasheets/Manuals | Printable datasheet for Human CD107b Antibody : FITC (OASB02642) |
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Tested Species Reactivity | Human |
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Predicted Species Reactivity | Human |
Product Format | Liquid. Phosphate buffered saline containing 0.1% sodium azide |
Clonality | Monoclonal |
Host | Mouse |
Conjugation | FITC |
Application | FC, ICC, IHC-F, IHC-P, WB |
Additional Information | Description: CD107b, also known as lysosomal-associated membrane protein 2 (LAMP-2), is a heavily glycosylated type I transmembrane protein that constitutes the major sialoglycoproteins on lysosomal membranes. It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains and is a ligand for E-selectin-mediated cell adhesion. CD107b is expressed in lysosomal/endosomal membranes and on the surface of activated platelets and some tumor cell lines including U937 and KG1a. LAMP-2 may function in protecting the inner surface of the lysosomal membrane by forming a barrier to lysosomal hydrolases. The upregulation of both CD107a and CD107b on the surface of tumor cell lines has been associated with their enhanced metastatic potential where they may increase adhesion to extracellular matrix and endothelium. |
Reconstitution and Storage | Store at 2-8C |
Immunogen | Human adherent peripheral blood cells |
Concentration | Lot specific |
Specificity | CD107b |
Gene Symbol | LAMP2, LAMP2, LAMP2 |
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Gene Full Name | lysosomal associated membrane protein 2 |
Alias Symbols | DND, LAMPB, CD107b, LAMP-2, LGP-96, LGP110 |
NCBI Gene Id | 3920; 695379; 103247358 |
Protein Name | lysosome-associated membrane glycoprotein 2 |
Description of Target | The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. Alternative splicing of this gene results in multiple transcript variants encoding distinct proteins. |
Uniprot ID | P13473, F7BCK9, A0A0D9S0F9 |
Protein Accession # | NP_001116078.1 |
Nucleotide Accession # | NM_001122606.1 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "Human CD107b Antibody : FITC (OASB02642)"?
The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human".
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How long will it take to receive "Human CD107b Antibody : FITC (OASB02642)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
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What buffer format is "Human CD107b Antibody : FITC (OASB02642)" provided in?
This item is provided in "Liquid. Phosphate buffered saline containing 0.1% sodium azide".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "Human CD107b Antibody : FITC (OASB02642)"?
This target may also be called "DND, LAMPB, CD107b, LAMP-2, LGP-96, LGP110" in publications.
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What is the shipping cost for "Human CD107b Antibody : FITC (OASB02642)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "Human CD107b Antibody : FITC (OASB02642)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "Human CD107b Antibody : FITC (OASB02642)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "Human CD107b Antibody : FITC (OASB02642)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "LAMP2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "LAMP2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "LAMP2"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "LAMP2"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "LAMP2"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "LAMP2"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.