Catalog No: OASB02639
Size:100T
Price: $329.00
SKU
OASB02639
Availability: Domestic: within 1-2 weeks delivery | International: 1-2 weeks
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  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for Human CD105C Antibody : APC (OASB02639)
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman
Product FormatLiquid. Phosphate buffered saline containing 0.1% sodium azide and a stabilizer
ClonalityMonoclonal
HostMouse
ConjugationAPC
ApplicationFC
Additional InformationDescription: CD105, also known as endoglin, is a 90 kDa type II transmembrane glycoprotein that is expressed on the cell surface as a disulfide-linked homodimer and is found on endothelial cells. CD105 is one of several receptors for the various isoforms of TGFbeta which in turn is one of a family of proteins involved in regulation of cell differentiation, migration of cells, and control on the immune response.
Reconstitution and StorageStore at 2-8C
ImmunogenAntigen preparation isolated from cell membranes of leukemia cells derived from a patient with non-T/non-B-cell acute lymphoblastic leukemia (ALL)
ConcentrationLot specific
SpecificityCD105
Gene SymbolENG, ENG
Gene Full Nameendoglin
Alias SymbolsEND, HHT1, ORW1
NCBI Gene Id2022; 100070421
Protein Nameendoglin
Description of TargetThis gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Uniprot IDP17813, U3MI26
Protein Accession #NP_000109.1
Nucleotide Accession #NM_000118.3
  1. What is the species homology for "Human CD105C Antibody : APC (OASB02639)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "Human CD105C Antibody : APC (OASB02639)"?

    This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".

  3. What buffer format is "Human CD105C Antibody : APC (OASB02639)" provided in?

    This item is provided in "Liquid. Phosphate buffered saline containing 0.1% sodium azide and a stabilizer".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "Human CD105C Antibody : APC (OASB02639)"?

    This target may also be called "END, HHT1, ORW1" in publications.

  5. What is the shipping cost for "Human CD105C Antibody : APC (OASB02639)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "Human CD105C Antibody : APC (OASB02639)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "Human CD105C Antibody : APC (OASB02639)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "Human CD105C Antibody : APC (OASB02639)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "ENG"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "ENG"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "ENG"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "ENG"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "ENG"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "ENG"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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