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Human CD105C Antibody : APC (OASB02639)

100 Tests
$259.00
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Tested Species Reactivity:
Human
Predicted Species Reactivity:
Horse
Product Format:
Liquid. Phosphate buffered saline containing 0.1% sodium azide and a stabilizer
Clonality:
Monoclonal
Host:
Mouse
Conjugation:
APC: Allophycocyanin
Application:
FC
Additional Information:
Description: CD105, also known as endoglin, is a 90 kDa type II transmembrane glycoprotein that is expressed on the cell surface as a disulfide-linked homodimer and is found on endothelial cells. CD105 is one of several receptors for the various isoforms of TGFbeta which in turn is one of a family of proteins involved in regulation of cell differentiation, migration of cells, and control on the immune response.
Reconstitution and Storage:
Store at 2-8C
Immunogen:
Antigen preparation isolated from cell membranes of leukemia cells derived from a patient with non-T/non-B-cell acute lymphoblastic leukemia (ALL)
Concentration:
Lot specific
Datasheets/Manuals:
Printable datasheet for OASB02639
Specificity:
CD105
Official Gene Full Name:
endoglin
Target:
ENG, ENG
Alias Symbols:
END, HHT1, ORW1
NCBI Gene Id:
2022; 100070421
Protein Name:
endoglin
Description of Target:
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Swissprot Id:
P17813, U3MI26
Protein Accession #:
NP_000109.1
Nucleotide Accession #:
NM_000118.3
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express ENG.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express ENG.

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