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MOG Antibody (OAPA00088)

500ug
$450.00
In Stock
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Product Format:
Sterile Filtered White lyophilized (freeze-dried) powder.
Clonality:
Monoclonal
Clone:
NYRMOG.
Isotype:
Mouse IgG1.
Host:
Mouse
Application:
ELISA, WB, IP, IHC
Reconstitution and Storage:
Reconstitution: Reconstitute with H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.
Storage: In lyophilized form, for long periods, store at 4C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20C.
Shipping Conditions: Antibody is shipped lyophilized at ambient temperature.
Gene Symbol:
MOG
NCBI Gene Id:
4340
Protein Name:
Myelin-oligodendrocyte glycoprotein
Swissprot Id:
Q16653
Protein Accession #:
NP_001008229.1
Alias Symbols:
MGC26137, MOG, MYELIN-OLIGODENDROCYTE GLYCOPROTEIN, MOG Antibody, myelin oligodendrocyte glycoprotein, Mouse Antibody
Replacement Item:
This antibody may replace item sc-166172 from Santa Cruz Biotechnology.
Description of Target:
MOG is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. MOG is involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified Minor component of the myelin sheath is involved in completion and/or maintenance of the myelin sheath and in cell- cell communication.
Purification:
Ion exchange column.
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express MOG.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express MOG.
Immunogen:
The immunogen for anti-MOG antibody: synthetic pMOG 35-55.
Concentration:
1 mg/ml in PBS (after reconstitution)
Datasheets/Manuals:
Printable datasheet for anti-MOG antibody - OAPA00088
Application Info:
Titer: By direct ELISA, 1:10,000 dilution will yield 0.5 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig (Jackson Laboratories).
Publications:

Buerth, C; Mausberg, AK; Heininger, MK; Hartung, HP; Kieseier, BC; Ernst, JF; Oral Tolerance Induction in Experimental Autoimmune Encephalomyelitis with Candida utilis Expressing the Immunogenic MOG35-55 Peptide. 11, e0155082 (2016). ELISA, WB, IP, IHC, 27159446

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