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MNDA Protein Lysate (APL10687)

Catalog#: APL10687
More Information
Additional InformationBuffer Formulation: 0.1M Tris-HCl (pH 6.8) buffer containing 0.2M DTT, 4% SDS, 0.2% Bromophenol blue and 20% Sucrose.
Reconstitution and StorageAdd 200ul of distilled water. Final concentration is 1 mg/ml. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Quality ControlThis product was tested on western blot.
Application : Western blot standard.
Observed Molecular Weight: 37
Expression system : Bacteria
TagGST in N-terminal
Datasheets/ManualsPrintable datasheet for anti-MNDA (APL10687) antibody
Gene SymbolMNDA
Alias SymbolsPYHIN3
NCBI Gene Id4332
Protein NameMyeloid cell nuclear differentiation antigen
Description of TargetThe myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons.
Swissprot IdP41218
Protein Accession #NP_002423.1
Nucleotide Accession #NM_002432.1
Molecular Weight37
Tissue ToolFind tissues and cell lines supported by DNA array analysis to express MNDA.
RNA SeqFind tissues and cell lines supported by RNA-seq analysis to express MNDA.
Protein InteractionsPRMT6; WHSC1L1; PRMT7; TP53; RBL2; RB1; HOXB2; CDK2; CDK1;
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