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MMP9 Antibody - C - terminal region (OABB00316)

100 ug
$229.00
In Stock
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Predicted Species Reactivity:
Human, Rat
Product Format:
Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3
Clonality:
Polyclonal
Isotype:
IgG
Host:
Rabbit
Application:
WB, IHC-FFPE
Reconstitution and Storage:
0.2ml of distilled water will yield a concentration of 500ug/ml. At -20C for one year. After reconstitution, at 4C for one month. It can also be aliquotted and stored frozen at -20C for a longer time. Avoid repeated freezing and thawing.
Replacement Item:
This antibody may replace item sc-10737, HPA001238
Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human MMP9 (689-705aa NQVDQVGYVTYDILQCP), different from the related mouse sequence by two amino acids, and from the related rat sequence by three amino acids.
Purification:
Immunogen affinity purified.
Predicted Homology Based on Immunogen Sequence:
Human; Rat
Datasheets/Manuals:
Printable datasheet for OABB00316
Specificity:
No cross reactivity with other proteins
Application Info:
Western Blot: 0.1-0.5 ug/ml. The detection limit for MMP9 is approximately 0.5 ng/lane under reducing conditions.
Target Reference:
1.Template:, 92kDa type IV collagenase)
2.Yuichiro Hirose et al. (May 2008). "A Functional Polymorphism in THBS2 that Affects Alternative Splicing and MMP Binding Is Associated with Lumbar-Disc Herniation".
Gene Symbol:
MMP9
Alias Symbols:
GELB, CLG4B, MMP-9, MANDP2,
NCBI Gene Id:
4318
Protein Name:
Matrix metalloproteinase-9
Description of Target:
Matrix metallopeptidase 9 (MMP-9), also known as 92 kDa type IV collagenase, 92 kDa gelatinase or gelatinase B (GELB), is an enzyme that in humans is encoded by the MMP9 gene. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling
Swissprot Id:
P14780
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express MMP9.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express MMP9.

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