MMP24 Antibody - middle region (OAAB16547)

Catalog No: OAAB16547

Size:400ul

Western blot analysis of MMP24 Antibody (Center) (Cat.# OAAB16547) in HL60 cell line lysates (35ug/lane). MMP24 (arrow) was detected using the purified Pab.

There is BioGPS gene expression data showing that MMP24 is expressed in HL60

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Clonality: Polyclonal
• Isotype: Ig
• Host: Rabbit
• Application: WB, IHC
• Additional Information: Precautions: MMP24 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
  Function: Activates progelatinase A. May also be a proteoglycanase involved in degradation of proteoglycans, such as dermatan sulfate and chondroitin sulfate proteoglycans. Cleaves partially fibronectin, but not collagen type I, nor laminin (By similarity)
  Cellular Location: Cell membrane; Single-pass type I membrane protein; Extracellular side (By similarity)
  Tissue Location: Predominantly expressed in brain, kidney, pancreas and lung. Overexpressed in a series of brain tumors, including astrocytomas and glioblastomas
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This MMP24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 396-425 amino acids from the Central region of human MMP24.
• Predicted Homology Based on Immunogen Sequence: Human; Mouse; Rat
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Sample Type Confirmation:

  There is BioGPS gene expression data showing that MMP24 is expressed in HL60

• Application Info: WB: 1:1000
  IHC-P: 1:50~100

Target Info

• Gene Symbol: MMP24
• Alias Symbols: MMP25, MMP-24, MT5MMP, MTMMP5, MT-MMP5, MT5-MMP, MT-MMP 5
• NCBI Gene Id: 10893
• Protein Name: Matrix metalloproteinase-24
• Description of Target: Purified Rabbit Polyclonal Antibody (Pab)
• Uniprot ID: Q9Y5R2
• Protein Accession #: NP_006681.1
• Molecular Weight: 73231 Da