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Datasheets/Manuals | Printable datasheet for anti-MMP2 (ARP97393_P050) antibody |
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Tested Species Reactivity | Human |
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Predicted Species Reactivity | Human |
Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Clonality | Polyclonal |
Host | Rabbit |
Application | WB |
Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human MMP2 |
Purification | Affinity purified |
Peptide Sequence | Synthetic peptide located within the following region: MARGALTGPLRALCLLGCLLSHAAAAPSPIIKFPGDVAPKTDKELAVQYL |
Concentration | 0.5 mg/ml |
Blocking Peptide | For anti-MMP2 (ARP97393_P050) antibody is Catalog # AAP97393 |
Gene Symbol | MMP2 |
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Gene Full Name | matrix metallopeptidase 2 |
Alias Symbols | CLG4, MONA, CLG4A, MMP-2, TBE-1, MMP-II |
NCBI Gene Id | 4313 |
Protein Name | CLG4, MONA, CLG4A, MMP-2, TBE-1, MMP-II |
Description of Target | This gene is a member of the matrix metalloproteinase (MMP) gene family, that are zinc-dependent enzymes capable of cleaving components of the extracellular matrix and molecules involved in signal transduction. The protein encoded by this gene is a gelatinase A, type IV collagenase, that contains three fibronectin type II repeats in its catalytic site that allow binding of denatured type IV and V collagen and elastin. Unlike most MMP family members, activation of this protein can occur on the cell membrane. This enzyme can be activated extracellularly by proteases, or, intracellulary by its S-glutathiolation with no requirement for proteolytical removal of the pro-domain. This protein is thought to be involved in multiple pathways including roles in the nervous system, endometrial menstrual breakdown, regulation of vascularization, and metastasis. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Uniprot ID | P08253 |
Protein Accession # | NP_001121363.1 |
Nucleotide Accession # | NM_001127891.2 |
Protein Size (# AA) | 660 |
Molecular Weight | 74 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "MMP2 Antibody - N-terminal region (ARP97393_P050)"?
The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human".
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How long will it take to receive "MMP2 Antibody - N-terminal region (ARP97393_P050)"?
This item is available "Domestic: within 24 hours delivery | International: 3-5 days".
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What buffer format is "MMP2 Antibody - N-terminal region (ARP97393_P050)" provided in?
This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "MMP2 Antibody - N-terminal region (ARP97393_P050)"?
This target may also be called "CLG4, MONA, CLG4A, MMP-2, TBE-1, MMP-II" in publications.
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What is the shipping cost for "MMP2 Antibody - N-terminal region (ARP97393_P050)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "MMP2 Antibody - N-terminal region (ARP97393_P050)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "MMP2 Antibody - N-terminal region (ARP97393_P050)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "74 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "MMP2 Antibody - N-terminal region (ARP97393_P050)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "MMP2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "MMP2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "MMP2"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "MMP2"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "MMP2"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "MMP2"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.