MMP19 Antibody - C-terminal region (OAAB16544)

Catalog No: OAAB16544

Size:400ul

Western blot analysis of hMMP19-R359 (Cat. # OAAB16544) in K562 cell line lysates (35ug/lane). MMP19 (arrow) was detected using the purified Pab.

MMP19 is supported by BioGPS gene expression data to be expressed in K562

Formalin-fixed and paraffin-embedded human breast carcinoma with MMP19 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Flow cytometric analysis of K562 cells using MMP19 Antibody (C-term) (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Product Info

• Predicted Species Reactivity: Human
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Clonality: Polyclonal
• Isotype: Ig
• Host: Rabbit
• Application: WB, IHC, FC
• Additional Information: Precautions: MMP19 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
  Function: Endopeptidase that degrades various components of the extracellular matrix, such as aggrecan and cartilage oligomeric matrix protein (comp), during development, haemostasis and pathological conditions (arthritic disease). May also play a role in neovascularization or angiogenesis. Hydrolyzes collagen type IV, laminin, nidogen, nascin-C isoform, fibronectin, and type I gelatin
  Cellular Location: Secreted, extracellular space, extracellular matrix (By similarity)
  Tissue Location: Expressed in mammary gland, placenta, lung, pancreas, ovary, small intestine, spleen, thymus, prostate, testis colon, heart and blood vessel walls. Not detected in brain and peripheral blood leukocytes. Also expressed in the synovial fluid of normal and rheumatoid patients
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This MMP19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-373 amino acids from the C-terminal region of human MMP19.
• Predicted Homology Based on Immunogen Sequence: Human
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Sample Type Confirmation:

  MMP19 is supported by BioGPS gene expression data to be expressed in K562

• Application Info: WB: 1:1000
  IHC-P: 1:50~100
  FC: 1:10~50

Target Info

• Gene Symbol: MMP19
• Alias Symbols: CODA, MMP18, RASI-1
• NCBI Gene Id: 4327
• Protein Name: Matrix metalloproteinase-19
• Description of Target: Purified Rabbit Polyclonal Antibody (Pab)
• Uniprot ID: Q99542
• Protein Accession #: NP_001259030.1
• Molecular Weight: 57357 Da