MMP16 Recombinant Protein (OPCD05328)

Catalog No: OPCD05328

MMP16 Recombinant Protein (OPCD05328) using SDS-PAGE

MMP16 Recombinant Protein (OPCD05328) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Ala351-Asn557
  Subcellular Location: Cell membrane; Single-pass type I membrane protein; Extracellular side. Secreted, extracellular space, extracellular matrix. Cell surfa
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: MMP16
• Gene Full Name: matrix metallopeptidase 16
• Alias Symbols: C8orf57;matrix metallopeptidase 16 (membrane-inserted);matrix metalloproteinase-16;membrane-type matrix metalloproteinase 3;membrane-type-3 matrix metalloproteinase;MMP-16;MMP-X2;MT3MMP;MT3-MMP;MT-MMP 3;MT-MMP2;MTMMP3;MT-MMP3;Putative transmembrane protein C8orf57.
• NCBI Gene Id: 4325
• Protein Name: Matrix metalloproteinase-16
• Description of Target: Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A. Involved in the matrix remodeling of blood vessels. Isoform short cleaves fibronectin and also collagen type III, but at lower rate. It has no effect on type I, II, IV and V collagen. However, upon interaction with CSPG4, it may be involved in degradation and invasion of type I collagen by melanoma cells.
• Uniprot ID: P51512
• Protein Accession #: NP_005932.2
• Nucleotide Accession #: NM_005941.4
• Protein Size (# AA): Ala351~Asn557
• Molecular Weight: 30kDa