Catalog No: OPED00095
Size:10UG
Price: $462.00
SKU
OPED00095
Availability: Domestic: within 1-2 week delivery | International: 1-2 week
Contact Us:
- Toll Free: 888-880-0001
- Phone: 858-552-6979
- Email: info@avivasysbio.com
Shipping Info:
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
Datasheets/Manuals | Printable datasheet for MMP14 Recombinant Protein (Human) (OPED00095) (OPED00095) |
---|
Predicted Species Reactivity | Homo sapiens|Human |
---|---|
Product Format | Liquid. In 50mM TRIS, pH 7.5, containing 5mM calcium chloride, 300mM sodium chloride, 20 uM zinc chloride, 0.5% Brij-35, and 30% glycerol. |
Host | E. Coli |
Reconstitution and Storage | Store at -80C |
Purification | Partially purified by single-step affinity chromatography and gel filtration. |
Biological Activity | ≥70 U/µg. One U=100 pmol/min at 37°C using the colorimetric thiopeptolide Ac-Pro-Leu-Gly-S-Leu-LeuGly-OEt (100 µM) as substrate |
Application Info | Useful tool to study enzyme kinetics, cleave target substrates, and screen for inhibitors. |
Gene Symbol | MMP14 |
---|---|
Gene Full Name | matrix metallopeptidase 14 |
Alias Symbols | matrix metallopeptidase 14 (membrane-inserted);matrix metalloproteinase-14;membrane type 1 metalloprotease;Membrane-type matrix metalloproteinase 1;membrane-type-1 matrix metalloproteinase;MMP-14;MMP-X1;MT1MMP;MT1-MMP;MT-MMP;MT-MMP 1;MTMMP1;WNCHRS. |
NCBI Gene Id | 4323 |
Protein Name | Matrix metalloproteinase-14 |
Description of Target | Endopeptidase that degrades various components of the extracellular matrix such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development (By similarity). May be involved in actin cytoskeleton reorganization by cleaving PTK7 (PubMed:20837484). Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro-MMP2 (PubMed:12714657). Cleaves ADGRB1 to release vasculostatin-40 which inhibits angiogenesis (PubMed:22330140). |
Uniprot ID | P50281 |
Protein Size (# AA) | Recombinant |
Molecular Weight | 65 kD |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
-
See our General FAQ page.
Write Your Own Review
We found other products you might like!