MMP11 Antibody - C-terminal region (OAAB16538)

Catalog No: OAAB16538

Size:400ul

Western blot analysis of anti-MMP11 Antibody (C-term) (Cat.# OAAB16538) in 293 cell line lysates (35ug/lane). MMP11(arrow) was detected using the purified Pab.

There is BioGPS gene expression data showing that MMP11 is expressed in HEK293

Product Info

• Predicted Species Reactivity: Human, Mouse
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
• Clonality: Polyclonal
• Isotype: Ig
• Host: Rabbit
• Application: WB
• Additional Information: Function: May play an important role in the progression of epithelial malignancies
  Cellular Location: Secreted, extracellular space, extracellular matrix
  Tissue Location: Specifically expressed in stromal cells of breast carcinomas
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This MMP11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 398-426 amino acids from the C-terminal region of human MMP11.
• Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Predicted Homology Based on Immunogen Sequence: Human; Mouse
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Sample Type Confirmation:

  There is BioGPS gene expression data showing that MMP11 is expressed in HEK293

• Intended Use: MMP11 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
• Application Info: WB: 1:1000

Target Info

• Gene Symbol: MMP11
• Alias Symbols: ST3, SL-3, STMY3
• NCBI Gene Id: 4320
• Protein Name: Stromelysin-3
• Description of Target: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP11 may play an important role in the progression of epithelial malignancies. It is specifically expressed in stromal cells of breast carcinomas.
• Uniprot ID: P24347
• Protein Accession #: NP_005931.2
• Molecular Weight: 54590 Da