MMP10 Antibody (OABB00338)

Catalog No: OABB00338

Size:100UG

Lane 1: Recombinant Human MMP-10 Protein 10ng
Lane 2: Recombinant Human MMP-10 Protein
Lane3: Recombinant Human MMP-10 Protein 2.5ng
Lane 4: Hela Cell Lysate
Lane 5: MK(55KD)

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Horse|Human|Monkey
• Product Format: Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
• Clonality: Polyclonal
• Clone: Polyclonal
• Isotype: Rabbit IgG
• Application: Western blot
• Additional Information: Notes: Tested Species: In-house tested species with positive results.
  Predicted Species: Species predicted to be fit for the product based on sequence similarities.
  Other applications have not been tested.
  Optimal dilutions should be determined by end users.
  
  Background: Stromelysin-2 also known as matrix metalloproteinase-10(MMP-10) or transin-2 is an enzyme that in humans is encoded by the MMP10 gene.Proteins of the matrix metalloproteinase(MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
  Background: Stromelysin-2 also known as matrix metalloproteinase-10 (MMP-10) or transin-2 is an enzyme that in humans is encoded by the MMP10 gene.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
• Reconstitution and Storage: 2°C to 8°C|-20°C
• Immunogen: Polypeptide
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Human
• Concentration: 500 ug/ml
• Specificity: No cross reactivity with other proteins.
• Application Info: Western blot: 0.1-0.5 ug/ml: Human
• Reference: 1.Muller D, Quantin B, Gesnel MC, Millon-Collard R, Abecassis J, Breathnach R (July 1988). "The
  collagenase gene family in humans consists of at least four members". Biochem. J. 253 (1): 187–92.
  2.Jung JY, Warter S, Rumpler Y (1990). "Localization of stromelysin 2 gene to the q22.3-23 region of
  chromosome 11 by in situ hybridization". Ann. Genet. 33 (1): 21–3.
• Storage Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
• Description: Rabbit IgG polyclonal antibody for Stromelysin-2(MMP10) detection. Tested with WB in Human.

Target Info

• Gene Symbol: MMP10
• Gene Full Name: matrix metallopeptidase 10
• Alias Symbols: matrix metalloprotease 10;matrix metalloproteinase 10 (stromelysin 2);matrix metalloproteinase-10;MMP-10;SL-2;STMY2;stromelysin-2;transin 2;Transin-2.
• NCBI Gene Id: 4319
• Protein Name: Stromelysin-2
• Description of Target: Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase.
• Uniprot ID: P09238
• Protein Accession #: NP_002416.1
• Nucleotide Accession #: NM_002425.2
• Molecular Weight: 54151 MW