MLPH Antibody - middle region (ARP96786_P050)

Catalog No: ARP96786_P050

Host: Rabbit
Target Name: MLPH
Sample Tissue: Human LN18 Whole Cell lysates
Antibody Dilution: 1ug/ml

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MLPH
• Purification: Affinity purified
• Peptide Sequence: Synthetic peptide located within the following region: SKSLTDESCSEKAAPHKAEGLEEADTGASGCHSHPEEQPTSISPSRHGAL
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-MLPH (ARP96786_P050) antibody is Catalog # AAP96786

Target Info

• Gene Symbol: MLPH
• Gene Full Name: melanophilin
• Alias Symbols: SLAC2-A
• NCBI Gene Id: 79083
• Protein Name: melanophilin
• Description of Target: This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Uniprot ID: Q9BV36
• Protein Accession #: NP_001035932.1
• Nucleotide Accession #: NM_001042467.2
• Protein Size (# AA): 600
• Molecular Weight: 66 kDa