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Catalog No: OASE00305-FITC
Size:100ug
Price: $429.00
SKU
OASE00305-FITC
Availability: Domestic: within 3-5 days delivery | International: 3-5 days
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Mitofusin 2 Antibody : FITC (OASE00305-FITC)

Datasheets/ManualsPrintable datasheet for OASE00305-FITC
Product Info
Predicted Species ReactivityMouse, Rat
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer.
ClonalityMonoclonal
CloneS153-5
IsotypeIgG2a
HostMouse
ConjugationFITC: Fluorescein Isothiocyanate
ApplicationWB, ICC, IHC
Additional InformationBackground Info: Detects a 90 kDa protein. No cross-reactivity against Mitofusin-1.
::Scientific Background: Mitofusin-2 (Mfn2) is a membrane protein of the mitochondria and is important in mitochondrial fusion in mammalian cells. Mfn2 activity has also been implicated in mitochondrial metabolism and the loss of Mfn2 may be the reason for certain metabolic modifications that are seen in individuals with obesity. Mfn2 has been associated with maintaining the membrane potential of the mitochondria. Mfn2 has been shown to hinder mitochondrial antiviral signaling by inhibiting production of type 1 interferons. Mfn2 is a p53-inducible target and involved in cell proliferation, apoptosis promotion and tumor suppression.
::Certificate of Analysis: 1ug/mL was sufficient for detection of Mitofusin-2 in 20 ug of mouse cardiac mitochondrial lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Reconstitution and StorageAll conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
ImmunogenFusion protein amino acids 370-600 (cytoplasmic N-terminus) of mouse Mitofusin-2 (Accession no. Q80U63)
Rat: 97% identity (226/231 amino acids identical)
Human: 92% identity (214/231 amino acids identical)
~55% identity with Mitofusin-1
PurificationProtein G Purified
Concentration1 mg/ml
Dilution1:1000 WB
Storage BufferPBS pH 7.4, 50% glycerol, 0.1% sodium azide
Gene SymbolMfn2
Gene Full Namemitofusin 2
Alias SymbolsFz, Fzo, D630023P19Rik
NCBI Gene Id170731
Uniprot IDQ80U63
Protein Accession #NP_573464.2
  1. What is the species homology for "Mitofusin 2 Antibody : FITC (OASE00305-FITC)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Mouse, Rat".

  2. How long will it take to receive "Mitofusin 2 Antibody : FITC (OASE00305-FITC)"?

    This item is available "Domestic: within 3-5 days delivery | International: 3-5 days".

  3. What buffer format is "Mitofusin 2 Antibody : FITC (OASE00305-FITC)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "Mitofusin 2 Antibody : FITC (OASE00305-FITC)"?

    This target may also be called "Fz, Fzo, D630023P19Rik" in publications.

  5. What is the shipping cost for "Mitofusin 2 Antibody : FITC (OASE00305-FITC)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "Mitofusin 2 Antibody : FITC (OASE00305-FITC)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "Mitofusin 2 Antibody : FITC (OASE00305-FITC)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "Mitofusin 2 Antibody : FITC (OASE00305-FITC)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "MFN2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "MFN2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "MFN2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "MFN2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "MFN2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "MFN2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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