MINOS1 Antibody - N-terminal region (OAAB18762)

Catalog No: OAAB18762

Size:400ul

Western blot analysis of lysate from mouse kidney tissue lysate, using MINOS1 Antibody (N-term) (Cat # OAAB18762). OAAB18762 was diluted at 1: 1000. A goat anti-rabbit IgG H&L (HRP) at 1: 10000 dilution was used as the secondary antibody. Lysate at 35ug.

Product Info

• Predicted Species Reactivity: Mouse
• Product Format: Liquid. PBS with 0.09% (W/V) sodium azide
• Clonality: Polyclonal
• Isotype: Rabbit Ig
• Host: Rabbit
• Application: WB, E
• Additional Information: Function: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
  Cellular Location: Mitochondrion inner membrane; Single-pass membrane protein. Note=The C-terminus is located in the intermembrane space (By similarity), while the location of the N-terminus has not been determined yet. As some programs predict the presence of 2 closely apposed membrane domains, it has been proposed that the protein may cross the membrane twice and that both termini may face the intermembrane space.
  
• Reconstitution and Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This MINOS1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1-33 amino acids from the N-terminal region of human MINOS1.
• Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Concentration: 0.5 mg/ml
• Intended Use: For research use only and not for use in diagnostic or therapeutic procedures.
• Application Info: WB: 1:1,000
  Optimal dilutions should be determined by the end user.
• Reference: Gregory S.G.,et al.Nature 441:315-321(2006).
  Alkhaja A.K.,et al.Mol. Biol. Cell 23:247-257(2012).
  Van Damme P.,et al.Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).

Target Info

• Gene Symbol: MINOS1
• Alias Symbols: Mi, Minos1, 2310028O11Rik
• NCBI Gene Id: 433771
• Description of Target: May play a role in mitochondrial architecture (By similarity).
• Uniprot ID: Q7TNS2
• Molecular Weight: 9 kDa