MIA2 Antibody - middle region (ARP47994_P050)

Catalog No: ARP47994_P050

WB Suggested Anti-CTAGE5 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Hela cell lysate

CTAGE5 antibody - middle region (ARP47994_P050)
Catalog Number: ARP47994_P050
Formalin Fixed Paraffin Embedded Tissue: Human Liver Tissue
Observed Staining: Membrane in hepatocytes
Primary Antibody Concentration: 1:100
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB, IHC
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CTAGE5
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 85%; Dog: 93%; Guinea Pig: 83%; Horse: 86%; Human: 100%; Pig: 93%; Rabbit: 86%; Rat: 93%
• Peptide Sequence: Synthetic peptide located within the following region: PPRGFPPYLPPRPGFFPPPPHSEGRSEFPSGLIPPSNEPATEHPEPQQET
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-MIA2 (ARP47994_P050) antibody is Catalog # AAP47994 (Previous Catalog # AAPS21311)
• Reference: Olsen,J.V., (2006) Cell 127 (3), 635-648

Target Info

• Gene Symbol: MIA2
• Gene Full Name: MIA SH3 domain ER export factor 2
• Alias Symbols: MEA6, MGEA, TALI, MGEA6, CTAGE5, MGEA11
• NCBI Gene Id: 4253
• Protein Name: cTAGE family member 5; melanoma inhibitory activity protein 2
• Description of Target: This gene encodes s receptor in the endoplasmic reticulum, which plays a role in the export of large pre-chylomicrons and pre-very low density lipoproteins (pre-VLDLs). Three major classes of transcripts are generated from this gene- melanoma inhibitory activity 2-specific transcripts, cTAGE family member 5-specific transcripts and transcripts that include exons from both these transcript species (TANGO1-like or TALI). Additionally, alternative splicing in these transcripts results in multiple transcript variants encoding multiple isoforms.
• Uniprot ID: O15320
• Protein Accession #: NP_976230
• Nucleotide Accession #: NM_203355
• Protein Size (# AA): 761
• Molecular Weight: 86kDa
• Protein Interactions: RASAL2; PSMA3; AES; MAGEB18; TTC23L; CCHCR1; SS18L1; EMILIN1; CEP57; DGCR6; Dlg4; UBC; GRB2; ALB;