MFN2 Antibody - middle region (OASG04516)

Catalog No: OASG04516

Size:100 uL

Western Blot using HUVEC

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB, IHC
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from the Internal region of human Mfn2.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Specificity: Mfn2 Polyclonal Antibody detects endogenous levels of Mfn2 protein.
• Application Info: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000;

Target Info

• Gene Symbol: MFN2
• Gene Full Name: mitofusin 2
• Alias Symbols: HSG, MARF, CMT2A, CPRP1, CMT2A2, HMSN6A, CMT2A2A, CMT2A2B
• NCBI Gene Id: 9927; 170731;
• Description of Target: This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.
• Uniprot ID: O95140, Q80U63, Q8R500
• Molecular Weight: 86 kDa