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- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
| Datasheets/Manuals | Printable datasheet for OAAQ00126 |
|---|
| Tested Species Reactivity | Human, Mouse |
|---|---|
| Predicted Species Reactivity | Mouse, Rat |
| Product Format | Liquid. 1X PBS, 0.02% NaN3, 50% Glycerol, 0.1% BSA. |
| Clonality | Monoclonal |
| Clone | MetY12341235-6F11 |
| Isotype | Rabbit IgG1k |
| Host | Rabbit |
| Conjugation | Unconjugated |
| Application | FC |
| Reconstitution and Storage | -20C |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Tyr1234/Tyr1235 of human phospho Met |
| Purification | Protein A+G |
| Target Post-Translational Modification | Phospho-Tyr1234/1235 |
| Application Info | 1ug/mL - 0.001ug/mL. It is recommended that the reagent be titrated for optimal performance for each application. See product image legends for additional information. |
| Reference | Cooper CS (January 1992). "The met oncogene: from detection by transfection to transmembrane receptor for hepatocyte growth factor". Oncogene. 7 (1): 3-7. Johnson M, Koukoulis G, Kochhar K, Kubo C, Nakamura T, Iyer A (Sep 1995). "Selective tumorigenesis in non-parenchymal liver epithelial cell lines by hepatocyte growth factor transfection". Cancer Letters. 96 (1): 37-48. Kochhar KS, Johnson ME, Volpert O, Iyer AP (1995). "Evidence for autocrine basis of transformation in NIH-3T3 cells transfected with met/HGF receptor gene". Growth Factors. 12 (4): 303-13. |
| Gene Symbol | MET |
|---|---|
| Gene Full Name | MET proto-oncogene, receptor tyrosine kinase |
| Alias Symbols | HGFR, AUTS9, RCCP2, c-Met, DFNB97 |
| NCBI Gene Id | 4233 |
| Protein Name | hepatocyte growth factor receptor |
| Description of Target | This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers. |
| Uniprot ID | P08581 |
| Protein Accession # | NP_000236.2 |
| Nucleotide Accession # | NM_000245.3 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "Human MET Antibody (Phospho-Tyr1234/1235) (OAAQ00126)"?
The tested species reactivity for this item is "Human, Mouse". This antibody is predicted to have homology to "Mouse, Rat".
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How long will it take to receive "Human MET Antibody (Phospho-Tyr1234/1235) (OAAQ00126)"?
This item is available "Domestic: within 1 week delivery | International: 1 week".
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What buffer format is "Human MET Antibody (Phospho-Tyr1234/1235) (OAAQ00126)" provided in?
This item is provided in "Liquid. 1X PBS, 0.02% NaN3, 50% Glycerol, 0.1% BSA.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "Human MET Antibody (Phospho-Tyr1234/1235) (OAAQ00126)"?
This target may also be called "HGFR, AUTS9, RCCP2, c-Met, DFNB97" in publications.
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What is the shipping cost for "Human MET Antibody (Phospho-Tyr1234/1235) (OAAQ00126)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "Human MET Antibody (Phospho-Tyr1234/1235) (OAAQ00126)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "Human MET Antibody (Phospho-Tyr1234/1235) (OAAQ00126)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "Human MET Antibody (Phospho-Tyr1234/1235) (OAAQ00126)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "MET"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "MET"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "MET"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "MET"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "MET"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "MET"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
