Size:100 ul
$229.00
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ARP36921_T100
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Conjugation Options

ARP36921_T100-FITC Conjugated

ARP36921_T100-HRP Conjugated

ARP36921_T100-Biotin Conjugated

MESP2 Antibody - C-terminal region (ARP36921_T100)

Catalog#: ARP36921_T100
Domestic: within 1-2 days delivery International: 1-2 days
More Information
Tested Species Reactivity Mouse
Predicted Species Reactivity Mouse, Rat
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality Polyclonal
Host Rabbit
Application WB
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-164989 from Santa Cruz Biotechnology.
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of mouse MESP2
Purification Protein A purified
Predicted Homology Based on Immunogen Sequence Mouse: 100%; Rat: 93%
Complete computational species homology data Anti-MESP2 (ARP36921_T100)
Peptide Sequence Synthetic peptide located within the following region: SCQRLQPQPQPQPQWGCWGHDAEVLSTSEDQGSSPALQLPVASPTPSSGL
Concentration Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide For anti-MESP2 (ARP36921_T100) antibody is Catalog # AAP36921 (Previous Catalog # AAPP08968)
Datasheets/Manuals Printable datasheet for anti-MESP2 (ARP36921_T100) antibody
Target Reference Morimoto,M., et al., (2005) Nature 435 (7040), 354-359
Publications

Leschik, J., Stefanovic, S., Brinon, B. & Pucéat, M. Cardiac commitment of primate embryonic stem cells. Nat. Protoc. 3, 1381-7 (2008). WB, Mouse, Rat 18772864

Gene Symbol MESP2
Official Gene Full Name Mesoderm posterior 2
Alias Symbols bHLHc6
NCBI Gene Id 17293
Protein Name Mesoderm posterior protein 2
Description of Target Somite boundaries formed during embryogenesis, at the interface between Notch1-activated and -repressed domains. Genetic and biochemical studies indicate that this interface is generated by suppression of Notch activity by mesoderm posterior 2 (Mesp2) through induction of the lunatic fringe gene (Lfng). It is proposed that the oscillation of Notch activity is arrested and translated in the wavefront by Mesp2.
Swissprot Id O08574
Protein Accession # NP_032615
Nucleotide Accession # NM_008589
Protein Size (# AA) 370
Molecular Weight 41kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express MESP2.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express MESP2.
Protein Interactions Lfng;
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