Aviva Systems Biology office will be closed for Good Friday - April 19, 2019.
Please go here for more info.

Search Antibody, Protein, and ELISA Kit Solutions

MESP2 Antibody - C-terminal region (ARP36921_T100)

100 ul
$229.00
In Stock
Request Bulk Order Quote

Conjugation Options

ARP36921_T100-FITC Conjugated

ARP36921_T100-HRP Conjugated

ARP36921_T100-Biotin Conjugated

Gene Symbol:
MESP2
Official Gene Full Name:
Mesoderm posterior 2
NCBI Gene Id:
17293
Protein Name:
Mesoderm posterior protein 2
Swissprot Id:
O08574
Protein Accession #:
NP_032615
Nucleotide Accession #:
NM_008589
Alias Symbols:
bHLHc6
Replacement Item:
This antibody may replace item sc-164989 from Santa Cruz Biotechnology.
Description of Target:
Somite boundaries formed during embryogenesis, at the interface between Notch1-activated and -repressed domains. Genetic and biochemical studies indicate that this interface is generated by suppression of Notch activity by mesoderm posterior 2 (Mesp2) through induction of the lunatic fringe gene (Lfng). It is proposed that the oscillation of Notch activity is arrested and translated in the wavefront by Mesp2.
Protein Size (# AA):
370
Molecular Weight:
41kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Protein A purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express MESP2.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express MESP2.
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of mouse MESP2
Predicted Species Reactivity:
Mouse, Rat
Tested Species Reactivity:
Mouse
Predicted Homology Based on Immunogen Sequence:
Mouse: 100%; Rat: 93%
Complete computational species homology data:
Anti-MESP2 (ARP36921_T100)
Peptide Sequence:
Synthetic peptide located within the following region: SCQRLQPQPQPQPQWGCWGHDAEVLSTSEDQGSSPALQLPVASPTPSSGL
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
Lfng;
Blocking Peptide:
For anti-MESP2 (ARP36921_T100) antibody is Catalog # AAP36921 (Previous Catalog # AAPP08968)
Datasheets/Manuals:
Printable datasheet for anti-MESP2 (ARP36921_T100) antibody
Target Reference:
Morimoto,M., et al., (2005) Nature 435 (7040), 354-359
Publications:

Leschik, J., Stefanovic, S., Brinon, B. & Pucéat, M. Cardiac commitment of primate embryonic stem cells. Nat. Protoc. 3, 1381-7 (2008). WB, Mouse, Rat 18772864

Product Reviews

Tell us what you think about this item!

Write A Review
    Please, wait...