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MESP1 antibody - N-terminal region (ARP39374_P050)

100 ul
$319.00
In Stock
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Conjugation Options

ARP39374_P050-FITC Conjugated

ARP39374_P050-HRP Conjugated

ARP39374_P050-Biotin Conjugated

Gene Symbol:
MESP1
NCBI Gene Id:
55897
Official Gene Full Name:
Mesoderm posterior 1 homolog (mouse)
Protein Name:
Mesoderm posterior protein 1
Swissprot Id:
Q9BRJ9
Protein Accession #:
NP_061140
Nucleotide Accession #:
NM_018670
Alias Symbols:
MGC10676, bHLHc5
Replacement Item:
This antibody may replace item sc-130461 from Santa Cruz Biotechnology.
Description of Target:
MESP1 is a transcription factor. MESP1 plays a role in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm. MESP1 defines the rostrocaudal patterning of the somites by participating in distinct Notch pathways.
Protein Size (# AA):
268
Molecular Weight:
28kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express MESP1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express MESP1.
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human MESP1
Tested Species Reactivity:
Human
Predicted Homology Based on Immunogen Sequence:
Dog: 85%; Human: 100%
Complete computational species homology data:
Anti-MESP1 (ARP39374_P050)
Peptide Sequence:
Synthetic peptide located within the following region: SLVSSPDSWGSTPADSPVASPARPGTLRDPRAPSVGRRGARSSRLGSGQR
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide:
For anti-MESP1 (ARP39374_P050) antibody is Catalog # AAP39374 (Previous Catalog # AAPP21385)
Datasheets/Manuals:
Printable datasheet for anti-MESP1 (ARP39374_P050) antibody
Target Reference:
David,R., (2008) Nat. Cell Biol. 10 (3), 338-345
Publications:

Hu, J; Wang, Y; Jiao, J; Liu, Z; Zhao, C; Zhou, Z; Zhang, Z; Forde, K; Wang, L; Wang, J; Baylink, DJ; Zhang, XB; Gao, S; Yang, B; Chen, YE; Ma, PX; Patient-specific cardiovascular progenitor cells derived from integration-free induced pluripotent stem cells for vascular tissue regeneration. 73, 51-9 (2015). WB, Dog, Human 26398309

Tan, Y; Han, P; Gu, Q; Chen, G; Wang, L; Ma, R; Wu, J; Feng, C; Zhang, Y; Wang, L; Hu, B; Li, W; Hao, J; Zhou, Q; Generation of Clinical-grade Functional Cardiomyocytes from Human Embryonic Stem Cells in Chemically Defined Conditions. , (2016). WB, Dog, Human 27943600

Tennis, M. A. et al. Prostacyclin inhibits non-small cell lung cancer growth by a frizzled 9-dependent pathway that is blocked by secreted frizzled-related protein 1. Neoplasia 12, 244-53 (2010). WB, Dog, Human 20335662

Cao, N. et al. Highly efficient induction and long-term maintenance of multipotent cardiovascular progenitors from human pluripotent stem cells under defined conditions. Cell Res. 23, 1119-32 (2013). WB, Dog, Human 23896987

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