- Tested Species Reactivity:
- Human
- Predicted Species Reactivity:
- Dog, Human
- Product Format:
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
- Clonality:
- Polyclonal
- Host:
- Rabbit
- Application:
- WB
- Reconstitution and Storage:
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
- Gene Symbol:
- MESP1
- Official Gene Full Name:
- Mesoderm posterior 1 homolog (mouse)
- NCBI Gene Id:
- 55897
- Protein Name:
- Mesoderm posterior protein 1
- Swissprot Id:
- Q9BRJ9
- Protein Accession #:
- NP_061140
- Nucleotide Accession #:
- NM_018670
- Alias Symbols:
- MGC10676, bHLHc5
- Replacement Item:
- This antibody may replace item sc-130461 from Santa Cruz Biotechnology.
- Description of Target:
- MESP1 is a transcription factor. MESP1 plays a role in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm. MESP1 defines the rostrocaudal patterning of the somites by participating in distinct Notch pathways.
- Protein Size (# AA):
- 268
- Molecular Weight:
- 28kDa
- Purification:
- Affinity Purified
- Tissue Tool:
- Find tissues and cell lines supported by DNA array analysis to express MESP1.
- RNA Seq:
- Find tissues and cell lines supported by RNA-seq analysis to express MESP1.
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N terminal region of human MESP1
- Predicted Homology Based on Immunogen Sequence:
- Dog: 85%; Human: 100%
- Complete computational species homology data:
- Anti-MESP1 (ARP39374_P050)
- Peptide Sequence:
- Synthetic peptide located within the following region: SLVSSPDSWGSTPADSPVASPARPGTLRDPRAPSVGRRGARSSRLGSGQR
- Concentration:
- Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
- Blocking Peptide:
- For anti-MESP1 (ARP39374_P050) antibody is Catalog # AAP39374 (Previous Catalog # AAPP21385)
- Datasheets/Manuals:
- Printable datasheet for anti-MESP1 (ARP39374_P050) antibody
- Target Reference:
- David,R., (2008) Nat. Cell Biol. 10 (3), 338-345
- Publications:
Cao, N. et al. Highly efficient induction and long-term maintenance of multipotent cardiovascular progenitors from human pluripotent stem cells under defined conditions. Cell Res. 23, 1119-32 (2013). WB, Dog, Human 23896987
Hu, J; Wang, Y; Jiao, J; Liu, Z; Zhao, C; Zhou, Z; Zhang, Z; Forde, K; Wang, L; Wang, J; Baylink, DJ; Zhang, XB; Gao, S; Yang, B; Chen, YE; Ma, PX; Patient-specific cardiovascular progenitor cells derived from integration-free induced pluripotent stem cells for vascular tissue regeneration. 73, 51-9 (2015). WB, Dog, Human 26398309
Tan, Y; Han, P; Gu, Q; Chen, G; Wang, L; Ma, R; Wu, J; Feng, C; Zhang, Y; Wang, L; Hu, B; Li, W; Hao, J; Zhou, Q; Generation of Clinical-grade Functional Cardiomyocytes from Human Embryonic Stem Cells in Chemically Defined Conditions. , (2016). WB, Dog, Human 27943600
Tennis, M. A. et al. Prostacyclin inhibits non-small cell lung cancer growth by a frizzled 9-dependent pathway that is blocked by secreted frizzled-related protein 1. Neoplasia 12, 244-53 (2010). WB, Dog, Human 20335662
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