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MER/SKY Antibody (Phospho-Tyr749/681) (OAAF00456)

100 ug
$379.00
In Stock
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Conjugation Options

OAAF00456-FITC Conjugated

OAAF00456-HRP Conjugated

OAAF00456-Biotin Conjugated

Gene Symbol:
TYRO3, MERTK
Official Gene Full Name:
Tyrosine-protein kinase receptor TYRO3
NCBI Gene Id:
7301, 10461
Protein Name:
Tyrosine-protein kinase receptor TYRO3
Swissprot Id:
Q12866, Q06418
Protein Accession #:
NP_006284.2
Alias Symbols:
C-mer; Receptor tyrosine kinase MerTK/ Tyrosine-protein kinase RSE; Tyrosine-protein kinase SKY; Tyrosine-protein kinase DTK; Protein-tyrosine kinase byk
Replacement Item:
This antibody may replace item sc-1094 from Santa Cruz Biotechnology.
Molecular Weight:
110 kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Application:
WB, IHC, ELISA
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express TYRO3.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express TYRO3.
Immunogen:
The antiserum was produced against synthesized peptide derived between 716-765 amino acids from human MER/SKY around the phosphorylation site of Tyr749/681.
Predicted Species Reactivity:
Human, Mouse, Rat
Product Format:
Liquid. PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Reconstitution and Storage:
Stable at -20°C for at least 1 year.
Concentration:
1 mg/ml
Datasheets/Manuals:
Printable datasheet for OAAF00456
Target Post-Translational Modification:
Phospho
Specificity:
MER/SKY (Phospho-Tyr749/681) antibody detects endogenous levels of MER/SKY only when phosphorylated at tyrosine 749/681.
Isotype:
IgG
Intended Use:
The product is for research use only, not for use in diagnostic or therapeutic procedures.
Application Info:
WB: 1:500~1000
IHC: 1:50~100
ELISA: 1:10000
Optimal dilutions should be determined by the end user.
Additional Information:
Modification Sites: H: Y749/681, M: Y744/671, R: Y744:671
Publications:

Kimani, SG; Kumar, S; Davra, V; Chang, YJ; Kasikara, C; Geng, K; Tsou, WI; Wang, S; Hoque, M; Boháč, A; Lewis-Antes, A; De Lorenzo, MS; Kotenko, SV; Birge, RB; Normalization of TAM post-receptor signaling reveals a cell invasive signature for Axl tyrosine kinase. 14, 19 (2016). WB, IHC, ELISA, Human, Mouse, Rat 27595981

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