MEN1 Antibody - N-terminal region (OAAB10047)

Catalog No: OAAB10047

Size:400ul

MEN1 Antibody (N-term) (Cat. #OAAB10047) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the MEN1 antibody detected the MEN1 protein (arrow).

Confocal immunofluorescent analysis of MEN1 Antibody (N-term)(Cat#OAAB10047) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue).

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Mouse, Rat
• Product Format: Liquid PBS with 0.09% (W/V) sodium azide.
• Clonality: Polyclonal
• Isotype: Ig
• Host: Rabbit
• Application: WB, IF, ELISA
  Cellular Location: Nucleus. Note=Concentrated in nuclear body- like structures. Relocates to the nuclear matrix upon gamma irradiation
  Tissue Location: Ubiquitous.
• Reconstitution and Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This MEN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 3-32 amino acids from the N-terminal region of human MEN1.
• Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Concentration: 0.32 mg/ml
• Application Info: WB: 1:1000
  IF: 1:10~50

Target Info

• Gene Symbol: MEN1
• Alias Symbols: MEAI, SCG2
• NCBI Gene Id: 4221
• Protein Name: Menin
• Description of Target: This gene encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type I. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Alternative splicing results in multiple transcript variants.
• Uniprot ID: O00255
• Protein Accession #: NP_000235.2